Cancer is a major public health problem in Myanmar and cancer registration activities are currently underway through both hospital-based and population-based approaches. The cancer statistics including cancer incidence and mortality data estimated by the population-based cancer registry are crucial in the development and evaluation of strategies for cancer prevention and control policies. This is the country's first-ever cancer statistics report at the regional level. The findings in this study are salient and have the potential to serve as important information for the National Cancer Control Program of Myanmar to formulate prevention and control strategies.