Canine parvovirus (CPV) is one of the most common infectious diseases of dogs and important viral cause of diarrhea in dogs. CPV infection is a relatively new disease that initially emerged in 1978 to a naïve canine population and spread rapidly with high morbidity and mortality. Because of the severity of the disease and its rapid spread through the canine population, CPV has aroused a great deal of public interest. The clinical manifestations of parvo are somewhat variable, but generally take the form of severe vomiting and diarrhoea. The diarrhoea may or may not contain blood. Additionally, affected dogs often exhibit a lack of appetite, depression, and fever. It is important to note that many dogs may not show every clinical sign, but vomiting and diarrhoea are the most common signs; vomiting usually begins first. Parvo may affect dogs of all ages, but is most common in dogs less than one year of age. This book illustrates the history, clinical signs, rapid diagnosis, epidemiology of canine parvovirus infection in pet and street dogs.