Capsaicin, the Pungent Principle in Hot Pepper - Szallasi, Arpad
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Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications is a comprehensive reference on the biology and pharmacological characteristics of this key active principle. Capsaicin is known for having diverse physiological and pathophysiological actions, ranging from appetite control through blood pressure regulation to pain relief and oncology. This book's content is presented in three sections. The first covers the historic development of research in the area, from the discovery and isolation, to the identification of its receptor, and antagonists. The…mehr

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Produktbeschreibung
Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications is a comprehensive reference on the biology and pharmacological characteristics of this key active principle. Capsaicin is known for having diverse physiological and pathophysiological actions, ranging from appetite control through blood pressure regulation to pain relief and oncology. This book's content is presented in three sections. The first covers the historic development of research in the area, from the discovery and isolation, to the identification of its receptor, and antagonists. The second part focuses on the biological effects and pharmacology, including nociception and pain, salivary secretion, body temperature regulation, and blood pressure regulation. The final part provides a current overview of the clinical applications and discusses possible future developments including desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications provides pharmacology researchers both in the lab and clinical settings with the needed information to apply and develop new treatments based on capsaicin's unique characteristics. Clinicians in pain management and cancer will benefit from the biology foundation provided by the author.
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Autorenporträt
Arpad Szallasi is a leading expert on the roles of TRP channels in health and disease. He was the first to provide a biochemical proof for the existence of the vanilloid (capsaicin) receptor, now known as TRPV1. Currently, he holds an Associate Professor position at the 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary. His research focuses on targeting of TRP channels for therapeutic purposes, with special emphasis on pain and inflammation. Arpad Szallasi obtained his MD degree Summa cum Laude from the Medical University School of Debrecen, Hungary (1984). He received his PhD degree in Pharmacology from the Karolinska Institute, Stockholm, Sweden (1995). Arpad Szallasi held several research positions both in academia (Karolinska Institute, Washington University, St. Louis, MO) and industry (Menarini Ricerche Sud, Pomezia, Italy) before pursuing a carrier in diagnostic pathology. Arpad Szallasi is a past President for the New Jersey Association of Blood Bank Professional and a former medical advisor to the American Red Cross.