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High Quality Content by WIKIPEDIA articles! A cardiac stress test is a medical test that indirectly reflects arterial blood flow to the heart during physical exercise. When compared to blood flow during rest, the test reflects imbalances of blood flow to the heart's left ventricular muscle tissue the part of the heart that performs the greatest amount of work pumping blood. The results may also be interpreted as a reflection on a person's overall physical fitness. The first standardized cardiac stress test was developed in 1929 by Arthur Master, a doctor at Mount Sinai Hospital in New York City.