The study focus on the cardiovascular disease and medicinal agents that affects the function of the heart and blood vessels. Drugs that act on the cardiovascular system are among the most widely used in medicine. Examples of disorders in which such drugs may be useful include hypertension ,angina pectoris ,heart failure ,and .Some examples of the drugs used in cardiovascular medicine include: Anticoagulants or blood thinner, Antiplatelet agents, Thrombolytic agents, Angiotensin-converting enzyme (ACE) inhibitors, Angiotensin II receptor blockers (ARBs),Beta blockers or beta-adrenergic blocking agents ,Calcium channel blockers, Diuretics and Vasodilators,Digoxin ,Statins.Commonly prescribed included cardiovascular drug such as Amlodipine,Diltiazem,Felodipine Nifedipine ,Nimodipine and Nisoldipine .Cardiovascular disease (CVD) is a general term that describes a disease of the heart or blood vessels. Blood flow to the heart, brain or body can be reduced because of a blood clot (thrombosis) build-up of fatty deposits inside an artery, leading to the artery hardening and narrowing (atherosclerosis).