Adolescents and youth are increasingly recognized as a priority on the global agenda as well as in national HIV polices; now action and resources must follow. While there are excellent examples of programmes that address the needs of young people, they are still not taken to the scale required to reach the targets set in the 2011 Political Declaration on HIV and AIDS. In order to increase the impact of the HIV response for adolescents and youth, the following strategies are needed:I. Know your local epidemic and scale-up evidence informed, youth- friendly programmes accordingly for adolescents and youth, especially young key populations and young people living with and affected by HIV; ensure programmes are tailored to the specific needs of girls, young women, boys and young men, included in national strategic plans, and appropriately costed and earmarked in national budgets.II. Expand efforts to integrate HIV programmes for young people, young key populations and young people living with HIV into a broader framework of sexual and reproductive health, ensure services are youth-friendly and explore