The central point of this book is the current understanding of processes accompanying embryonic transitions, in which cell cycle machinery is implicated. The authors explain numerous questions of how the basic cell cycle events are controlled at the cellular level, how the embryonic development is prepared during oogenesis and oocyte maturation, and how the interplay between cell cycle controlling machinery and the developmental program is brought to action from fertilization till aging and pathologies of the latter. The logical sequence of chapters fluently guides the reader through the world…mehr
The central point of this book is the current understanding of processes accompanying embryonic transitions, in which cell cycle machinery is implicated. The authors explain numerous questions of how the basic cell cycle events are controlled at the cellular level, how the embryonic development is prepared during oogenesis and oocyte maturation, and how the interplay between cell cycle controlling machinery and the developmental program is brought to action from fertilization till aging and pathologies of the latter. The logical sequence of chapters fluently guides the reader through the world of cell cycle and embryogenesis, and is bound to stimulate a very rich discussion.
Artikelnr. des Verlages: 80015599, 978-3-642-19064-3
2011
Seitenzahl: 604
Erscheinungstermin: 2. Juni 2011
Englisch
Abmessung: 241mm x 160mm x 37mm
Gewicht: 1006g
ISBN-13: 9783642190643
ISBN-10: 3642190642
Artikelnr.: 32689113
Inhaltsangabe
Experimental systems to explore life origin: perspectives for understanding primitive mechanisms of cell division. Evolution of bet-hedging mechanisms in cell cycle and embryo development stimulated by weak linkage of stochastic processes. Mechanics of cell shape regulation during the cell cycle. The spindle assembly checkpoint: clock or domino? Cell-size-dependent control of organelle sizes during development. The first cell cycle of the C. elegans embryo. Spatial and temporal control of an asymmetric cell division. EGG Molecules Couple the Oocyte-to-Embryo Transition with Cell Cycle Progression. Cell cycle in ascidian eggs and embryos. Regulatory Pathways Coordinating Cell Cycle Progression in Early Xenopus Development. Control of DNA replication by Cyclin-Dependent Kinases in development. Greatwall kinase, ARPP-19 and protein phosphatase 2A: shifting the mitosis paradigm. The Role of RanGTP Gradient in Vertebrate Oocyte Maturation. Cell Cycle Control of Germ Cell Differentiation. Protein kinases and protein phosphatases that regulate meiotic maturation in mouse oocytes. Anaphase-Promoting Complex control in female mouse meiosis. Established and novel Cdk/cyclin complexes regulating the cell cycle and development. Function of the A-type Cyclins during Gametogenesis and Early Embryogenesis. Cell cycle adaptations and maintenance of genomic integrity in embryonic stem cells and induced pluripotent stem cells. Cell cycle regulation by microRNAs in stem cells. Cell cycle regulation during proliferation and differentiation of mammalian muscle precursor cells. Drosophila neural stem cells: cell cycle control of self-renewal, differentiation and termination in brain development. Control of neuronal ploidy during vertebrate development. Cell Cycle Deregulation in the Neurons of Alzheimer's Disease.
Experimental systems to explore life origin: perspectives for understanding primitive mechanisms of cell division. Evolution of bet-hedging mechanisms in cell cycle and embryo development stimulated by weak linkage of stochastic processes. Mechanics of cell shape regulation during the cell cycle. The spindle assembly checkpoint: clock or domino? Cell-size-dependent control of organelle sizes during development. The first cell cycle of the C. elegans embryo. Spatial and temporal control of an asymmetric cell division. EGG Molecules Couple the Oocyte-to-Embryo Transition with Cell Cycle Progression. Cell cycle in ascidian eggs and embryos. Regulatory Pathways Coordinating Cell Cycle Progression in Early Xenopus Development. Control of DNA replication by Cyclin-Dependent Kinases in development. Greatwall kinase, ARPP-19 and protein phosphatase 2A: shifting the mitosis paradigm. The Role of RanGTP Gradient in Vertebrate Oocyte Maturation. Cell Cycle Control of Germ Cell Differentiation. Protein kinases and protein phosphatases that regulate meiotic maturation in mouse oocytes. Anaphase-Promoting Complex control in female mouse meiosis. Established and novel Cdk/cyclin complexes regulating the cell cycle and development. Function of the A-type Cyclins during Gametogenesis and Early Embryogenesis. Cell cycle adaptations and maintenance of genomic integrity in embryonic stem cells and induced pluripotent stem cells. Cell cycle regulation by microRNAs in stem cells. Cell cycle regulation during proliferation and differentiation of mammalian muscle precursor cells. Drosophila neural stem cells: cell cycle control of self-renewal, differentiation and termination in brain development. Control of neuronal ploidy during vertebrate development. Cell Cycle Deregulation in the Neurons of Alzheimer's Disease.
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