Apoptosis is a type of cell death that plays an important role in regulating the growth, development and immune response, and cleansing abnormal cells. This process is also an important way to maintain the number of cells in the body for survival, and activating its mechanism to control the cancer process is essential. Understanding the apoptotic mechanism is very important and it will help to understand the pathogenesis of the conditions resulting from apoptotic disturbances and also the development of the use of drugs that target genes and apoptosis pathways.