Examines the current state and future prospects of haematopoietic cell therapy, including gene therapy and immunotherapy.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Part I. Aspects of Hematopoiesis: 1. Overview of hematopoiesis and review of cells needed for hematopoietic reconstitution 2. Review of cells important for adoptive cellular immunotherapy 3. Potential uses of defined cell populations 4. Progenitor cell assays 5. Flow cytometric techniques 6. Principles of gene therapy 7. Sources of progenitor cells 8. Chemotherapy approaches to mobilization of progenitor cells 9. Cytokine approaches to mobilization of progenitor cells 10. Stem cell isolation 11. Methods of cell selection using monoclonal antibodies 12. Magnetic approaches to cell separation 13. Growth factors and ex-vivo expansion of hematopoietic progenitor cells 14. Bioreactors for expansion 15. Purging of malignant cells Part II. Current Clinical Approaches: 16. What can be achieved without cell therapy 17. Clinical potential of hematopoietic growth-factor support for high-dose chemotherapy 18. Review of high-dose chemotherapy requiring cellular support in solid tumors 19. Review of high-dose chemotherapy requiring cellular support in hematological malignancies 20. Review of the potential use of cell therapy in leukemia Part III. Future Clinical Applications: 21. Clinical gene therapy 22. Correction of inborn errors 23. Cellular therapy approaches to the treatment of AIDS Part IV. Experimental and Clinical Cellular Immunotherapy: 24. Adoptive immunotherapy with T cells 25. Cellular adoptive immunotherapy with natural killer cells 26. Autologous tumor cell vaccines 27. Allogeneic cellular vaccines against tumors 28. Neutrophil transfusions for treatment of infections 29. Experimental and clinical cellular immunotherapy in bone-marrow transplantation 30. Donor lymphocyte therapy in bone-marrow transplantation 31. Graft-versus-leukemia effect in bone-marrow transplantation.
Part I. Aspects of Hematopoiesis: 1. Overview of hematopoiesis and review of cells needed for hematopoietic reconstitution 2. Review of cells important for adoptive cellular immunotherapy 3. Potential uses of defined cell populations 4. Progenitor cell assays 5. Flow cytometric techniques 6. Principles of gene therapy 7. Sources of progenitor cells 8. Chemotherapy approaches to mobilization of progenitor cells 9. Cytokine approaches to mobilization of progenitor cells 10. Stem cell isolation 11. Methods of cell selection using monoclonal antibodies 12. Magnetic approaches to cell separation 13. Growth factors and ex-vivo expansion of hematopoietic progenitor cells 14. Bioreactors for expansion 15. Purging of malignant cells Part II. Current Clinical Approaches: 16. What can be achieved without cell therapy 17. Clinical potential of hematopoietic growth-factor support for high-dose chemotherapy 18. Review of high-dose chemotherapy requiring cellular support in solid tumors 19. Review of high-dose chemotherapy requiring cellular support in hematological malignancies 20. Review of the potential use of cell therapy in leukemia Part III. Future Clinical Applications: 21. Clinical gene therapy 22. Correction of inborn errors 23. Cellular therapy approaches to the treatment of AIDS Part IV. Experimental and Clinical Cellular Immunotherapy: 24. Adoptive immunotherapy with T cells 25. Cellular adoptive immunotherapy with natural killer cells 26. Autologous tumor cell vaccines 27. Allogeneic cellular vaccines against tumors 28. Neutrophil transfusions for treatment of infections 29. Experimental and clinical cellular immunotherapy in bone-marrow transplantation 30. Donor lymphocyte therapy in bone-marrow transplantation 31. Graft-versus-leukemia effect in bone-marrow transplantation.
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