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The treatment of bone defects is an ongoing challenge in traumatology and orthopedics. In order to contribute to the repair of musculoskeletal injuries, bone cements and bone grafts are used. These materials must have specific characteristics and properties.Cement is an acrylic resin prepared from two components which, when mixed, produce a polymerization reaction. They have important functions and can be applied in almost all joints. This is a dynamic compound whose properties will vary over time. Bone grafts are tissues with living donor cells capable of surviving in the recipient organism. It has important biological and mechanical functions related to the number of living cells.Both cements and bone grafts have a high and frequent use in orthopedic surgery and traumatology derived mainly from the multiple benefits they provide to patients in the treatment of various musculoskeletal pathologies.