Cerebral Small Vessel Disease
Herausgeber: Pantoni, Leonardo; Gorelick, Philip B
Cerebral Small Vessel Disease
Herausgeber: Pantoni, Leonardo; Gorelick, Philip B
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Small vessel disease is an important frontier in neurology; about 25% of strokes are classified as small vessel, and SVD is the most common cause of vascular cognitive impairment. The risk of developing SVD increases with age, making this a growing concern for countries with aging populations. Despite this, there has been a paucity of information about its causes, diagnosis, prevention and treatment. This volume brings together contributions from leading international experts in the field and discusses pathogenesis, pathophysiology, clinical and radiologic manifestations, prevention and…mehr
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Small vessel disease is an important frontier in neurology; about 25% of strokes are classified as small vessel, and SVD is the most common cause of vascular cognitive impairment. The risk of developing SVD increases with age, making this a growing concern for countries with aging populations. Despite this, there has been a paucity of information about its causes, diagnosis, prevention and treatment. This volume brings together contributions from leading international experts in the field and discusses pathogenesis, pathophysiology, clinical and radiologic manifestations, prevention and treatment modalities, and future directions for research and practice. Genetic forms of SVD are discussed, as well as the rapid development of neuroimaging techniques as tools for screening and treatment. This authoritative book is essential reading for neurologists, stroke physicians, geriatricians, and interventional neuroradiologists, as well as researchers in the fields of aging and dementia.
Produktdetails
- Produktdetails
- Verlag: Cambridge University Press
- Seitenzahl: 371
- Erscheinungstermin: 23. Juni 2014
- Englisch
- Abmessung: 254mm x 192mm x 22mm
- Gewicht: 991g
- ISBN-13: 9781107031661
- ISBN-10: 1107031664
- Artikelnr.: 40873902
- Verlag: Cambridge University Press
- Seitenzahl: 371
- Erscheinungstermin: 23. Juni 2014
- Englisch
- Abmessung: 254mm x 192mm x 22mm
- Gewicht: 991g
- ISBN-13: 9781107031661
- ISBN-10: 1107031664
- Artikelnr.: 40873902
Preface; Part I. Classification, Pathology and Basic Aspects: 1. Definition
and classification of small vessel diseases Leonardo Pantoni; 2. Pathology
of cerebral small vessel disease Jun Ogata, Hiromichi Yamanishi and Hatsue
Ishibashi-Ueda; 3. Pathological aspects of the ischemic consequences of
small vessel disease on brain parenchyma Margaret Esiri and Elisabet
Englund; 4. Pathological aspects of the hemorrhagic consequences of small
vessel diseases on the brain Johannes Attems and Kurt A. Jellinger; 5.
Experimental animal models of cerebral small vessel disease Atticus H.
Hainsworth and Hugh S. Markus; 6. Sporadic small vessels disease:
pathogenic aspects Joanna M. Wardlaw and Leonardo Pantoni; 7. Pathogenic
aspects of hereditary small vessel disease of the brain Anne Joutel; 8.
Hereditary cerebral small vessel disease and role of genetic factors
Christian Opherk and Martin Dichgans; 9. The link between large artery
aging and cerebral small vessel disease Angelo Scuteri and Edward G.
Lakatta; 10. The neurovascular unit and possible influences on cerebral
small vessel disease Gregory J. del Zoppo, Yoshikane Izawa and Brian T.
Hawkins; Part II. Neuroimaging and Laboratory Aspects: 11. Conventional
brain imaging of white matter lesions Franz Fazekas, Christian Enzinger,
Stefan Ropele and Reinhold Schmidt; 12. Conventional imaging of lacunar
infarcts Eric Jouvent and Hugues Chabriat; 13. Imaging of hemorrhagic
cerebral small vessel disease Jennifer Linn, Steven Greenberg and Anand
Viswanathan; 14. Nonconventional MR techniques for imaging cerebral small
vessel disease David Nyenhuis and Glenn T. Stebbins; 15. Cerebral
hemodynamics in cerebral small vessel disease Hugh S. Markus, Charlotte L.
Allan and Klaus P. Ebmeier; 16. Markers of endothelial dysfunction,
oxidative stress and inflammation in cerebral small vessels disease
Francesca Pescini and Rosanna Abbate; 17. Cerebral small vessel disease:
cerebrospinal fluid aspects Anders Wallin and Maria Bjerke; Part III.
Clinical Aspects of Cerebral Small Vessel Disease: 18. Acute stroke
syndromes caused by small vessel disease Mark I. Boulos, Ranjith K. Menon,
Richard I. Aviv, Sandra E. Black and Richard H. Swartz; 19. Cognitive
consequences of cerebral small vessel disease José M. Ferro, Ana Verdelho
and Sofia Madureira; 20. Motor, stance and balance consequences of cerebral
small vessel diseases H. Baezner, Christian Blahak and Michael G.
Hennerici; 21. Psychiatric consequences of small vessel disease Perminder
S. Sachdev and Sharon Reutens; 22. Consequences of cerebral small vessel
disease: disability, mortality and prognosis Anna Poggesi, Leonardo Pantoni
and Domenico Inzitari; 23. Clinical aspects of genetic forms of small
vessel disease Maria Teresa Dotti and Antonio Federico; 24. Interaction
between cerebral small vessel disease and neurodegenerative changes Wiesje
M. van der Flier and Raj Kalaria; Part IV. Therapeutic Aspects: Prevention,
Future Directions, and Possibilities: 25. Risk factors as possible targets
for prevention of small vessel disease Vincent Mok, Philip B. Gorelick and
Christopher Chen; 26. Treatment approaches for lacunar strokes Makoto
Nakajima, Thalia Field and Oscar R. Benavente; 27. Cerebral small vessels
disease imaging as a surrogate marker for clinical trials Reinhold Schmidt,
Margherita Cavalieri and Marisa Loitfelder; 28. Cerebral small vessel
disease: a look to the future Philip B. Gorelick and Leonardo Pantoni;
Index.
and classification of small vessel diseases Leonardo Pantoni; 2. Pathology
of cerebral small vessel disease Jun Ogata, Hiromichi Yamanishi and Hatsue
Ishibashi-Ueda; 3. Pathological aspects of the ischemic consequences of
small vessel disease on brain parenchyma Margaret Esiri and Elisabet
Englund; 4. Pathological aspects of the hemorrhagic consequences of small
vessel diseases on the brain Johannes Attems and Kurt A. Jellinger; 5.
Experimental animal models of cerebral small vessel disease Atticus H.
Hainsworth and Hugh S. Markus; 6. Sporadic small vessels disease:
pathogenic aspects Joanna M. Wardlaw and Leonardo Pantoni; 7. Pathogenic
aspects of hereditary small vessel disease of the brain Anne Joutel; 8.
Hereditary cerebral small vessel disease and role of genetic factors
Christian Opherk and Martin Dichgans; 9. The link between large artery
aging and cerebral small vessel disease Angelo Scuteri and Edward G.
Lakatta; 10. The neurovascular unit and possible influences on cerebral
small vessel disease Gregory J. del Zoppo, Yoshikane Izawa and Brian T.
Hawkins; Part II. Neuroimaging and Laboratory Aspects: 11. Conventional
brain imaging of white matter lesions Franz Fazekas, Christian Enzinger,
Stefan Ropele and Reinhold Schmidt; 12. Conventional imaging of lacunar
infarcts Eric Jouvent and Hugues Chabriat; 13. Imaging of hemorrhagic
cerebral small vessel disease Jennifer Linn, Steven Greenberg and Anand
Viswanathan; 14. Nonconventional MR techniques for imaging cerebral small
vessel disease David Nyenhuis and Glenn T. Stebbins; 15. Cerebral
hemodynamics in cerebral small vessel disease Hugh S. Markus, Charlotte L.
Allan and Klaus P. Ebmeier; 16. Markers of endothelial dysfunction,
oxidative stress and inflammation in cerebral small vessels disease
Francesca Pescini and Rosanna Abbate; 17. Cerebral small vessel disease:
cerebrospinal fluid aspects Anders Wallin and Maria Bjerke; Part III.
Clinical Aspects of Cerebral Small Vessel Disease: 18. Acute stroke
syndromes caused by small vessel disease Mark I. Boulos, Ranjith K. Menon,
Richard I. Aviv, Sandra E. Black and Richard H. Swartz; 19. Cognitive
consequences of cerebral small vessel disease José M. Ferro, Ana Verdelho
and Sofia Madureira; 20. Motor, stance and balance consequences of cerebral
small vessel diseases H. Baezner, Christian Blahak and Michael G.
Hennerici; 21. Psychiatric consequences of small vessel disease Perminder
S. Sachdev and Sharon Reutens; 22. Consequences of cerebral small vessel
disease: disability, mortality and prognosis Anna Poggesi, Leonardo Pantoni
and Domenico Inzitari; 23. Clinical aspects of genetic forms of small
vessel disease Maria Teresa Dotti and Antonio Federico; 24. Interaction
between cerebral small vessel disease and neurodegenerative changes Wiesje
M. van der Flier and Raj Kalaria; Part IV. Therapeutic Aspects: Prevention,
Future Directions, and Possibilities: 25. Risk factors as possible targets
for prevention of small vessel disease Vincent Mok, Philip B. Gorelick and
Christopher Chen; 26. Treatment approaches for lacunar strokes Makoto
Nakajima, Thalia Field and Oscar R. Benavente; 27. Cerebral small vessels
disease imaging as a surrogate marker for clinical trials Reinhold Schmidt,
Margherita Cavalieri and Marisa Loitfelder; 28. Cerebral small vessel
disease: a look to the future Philip B. Gorelick and Leonardo Pantoni;
Index.
Preface; Part I. Classification, Pathology and Basic Aspects: 1. Definition
and classification of small vessel diseases Leonardo Pantoni; 2. Pathology
of cerebral small vessel disease Jun Ogata, Hiromichi Yamanishi and Hatsue
Ishibashi-Ueda; 3. Pathological aspects of the ischemic consequences of
small vessel disease on brain parenchyma Margaret Esiri and Elisabet
Englund; 4. Pathological aspects of the hemorrhagic consequences of small
vessel diseases on the brain Johannes Attems and Kurt A. Jellinger; 5.
Experimental animal models of cerebral small vessel disease Atticus H.
Hainsworth and Hugh S. Markus; 6. Sporadic small vessels disease:
pathogenic aspects Joanna M. Wardlaw and Leonardo Pantoni; 7. Pathogenic
aspects of hereditary small vessel disease of the brain Anne Joutel; 8.
Hereditary cerebral small vessel disease and role of genetic factors
Christian Opherk and Martin Dichgans; 9. The link between large artery
aging and cerebral small vessel disease Angelo Scuteri and Edward G.
Lakatta; 10. The neurovascular unit and possible influences on cerebral
small vessel disease Gregory J. del Zoppo, Yoshikane Izawa and Brian T.
Hawkins; Part II. Neuroimaging and Laboratory Aspects: 11. Conventional
brain imaging of white matter lesions Franz Fazekas, Christian Enzinger,
Stefan Ropele and Reinhold Schmidt; 12. Conventional imaging of lacunar
infarcts Eric Jouvent and Hugues Chabriat; 13. Imaging of hemorrhagic
cerebral small vessel disease Jennifer Linn, Steven Greenberg and Anand
Viswanathan; 14. Nonconventional MR techniques for imaging cerebral small
vessel disease David Nyenhuis and Glenn T. Stebbins; 15. Cerebral
hemodynamics in cerebral small vessel disease Hugh S. Markus, Charlotte L.
Allan and Klaus P. Ebmeier; 16. Markers of endothelial dysfunction,
oxidative stress and inflammation in cerebral small vessels disease
Francesca Pescini and Rosanna Abbate; 17. Cerebral small vessel disease:
cerebrospinal fluid aspects Anders Wallin and Maria Bjerke; Part III.
Clinical Aspects of Cerebral Small Vessel Disease: 18. Acute stroke
syndromes caused by small vessel disease Mark I. Boulos, Ranjith K. Menon,
Richard I. Aviv, Sandra E. Black and Richard H. Swartz; 19. Cognitive
consequences of cerebral small vessel disease José M. Ferro, Ana Verdelho
and Sofia Madureira; 20. Motor, stance and balance consequences of cerebral
small vessel diseases H. Baezner, Christian Blahak and Michael G.
Hennerici; 21. Psychiatric consequences of small vessel disease Perminder
S. Sachdev and Sharon Reutens; 22. Consequences of cerebral small vessel
disease: disability, mortality and prognosis Anna Poggesi, Leonardo Pantoni
and Domenico Inzitari; 23. Clinical aspects of genetic forms of small
vessel disease Maria Teresa Dotti and Antonio Federico; 24. Interaction
between cerebral small vessel disease and neurodegenerative changes Wiesje
M. van der Flier and Raj Kalaria; Part IV. Therapeutic Aspects: Prevention,
Future Directions, and Possibilities: 25. Risk factors as possible targets
for prevention of small vessel disease Vincent Mok, Philip B. Gorelick and
Christopher Chen; 26. Treatment approaches for lacunar strokes Makoto
Nakajima, Thalia Field and Oscar R. Benavente; 27. Cerebral small vessels
disease imaging as a surrogate marker for clinical trials Reinhold Schmidt,
Margherita Cavalieri and Marisa Loitfelder; 28. Cerebral small vessel
disease: a look to the future Philip B. Gorelick and Leonardo Pantoni;
Index.
and classification of small vessel diseases Leonardo Pantoni; 2. Pathology
of cerebral small vessel disease Jun Ogata, Hiromichi Yamanishi and Hatsue
Ishibashi-Ueda; 3. Pathological aspects of the ischemic consequences of
small vessel disease on brain parenchyma Margaret Esiri and Elisabet
Englund; 4. Pathological aspects of the hemorrhagic consequences of small
vessel diseases on the brain Johannes Attems and Kurt A. Jellinger; 5.
Experimental animal models of cerebral small vessel disease Atticus H.
Hainsworth and Hugh S. Markus; 6. Sporadic small vessels disease:
pathogenic aspects Joanna M. Wardlaw and Leonardo Pantoni; 7. Pathogenic
aspects of hereditary small vessel disease of the brain Anne Joutel; 8.
Hereditary cerebral small vessel disease and role of genetic factors
Christian Opherk and Martin Dichgans; 9. The link between large artery
aging and cerebral small vessel disease Angelo Scuteri and Edward G.
Lakatta; 10. The neurovascular unit and possible influences on cerebral
small vessel disease Gregory J. del Zoppo, Yoshikane Izawa and Brian T.
Hawkins; Part II. Neuroimaging and Laboratory Aspects: 11. Conventional
brain imaging of white matter lesions Franz Fazekas, Christian Enzinger,
Stefan Ropele and Reinhold Schmidt; 12. Conventional imaging of lacunar
infarcts Eric Jouvent and Hugues Chabriat; 13. Imaging of hemorrhagic
cerebral small vessel disease Jennifer Linn, Steven Greenberg and Anand
Viswanathan; 14. Nonconventional MR techniques for imaging cerebral small
vessel disease David Nyenhuis and Glenn T. Stebbins; 15. Cerebral
hemodynamics in cerebral small vessel disease Hugh S. Markus, Charlotte L.
Allan and Klaus P. Ebmeier; 16. Markers of endothelial dysfunction,
oxidative stress and inflammation in cerebral small vessels disease
Francesca Pescini and Rosanna Abbate; 17. Cerebral small vessel disease:
cerebrospinal fluid aspects Anders Wallin and Maria Bjerke; Part III.
Clinical Aspects of Cerebral Small Vessel Disease: 18. Acute stroke
syndromes caused by small vessel disease Mark I. Boulos, Ranjith K. Menon,
Richard I. Aviv, Sandra E. Black and Richard H. Swartz; 19. Cognitive
consequences of cerebral small vessel disease José M. Ferro, Ana Verdelho
and Sofia Madureira; 20. Motor, stance and balance consequences of cerebral
small vessel diseases H. Baezner, Christian Blahak and Michael G.
Hennerici; 21. Psychiatric consequences of small vessel disease Perminder
S. Sachdev and Sharon Reutens; 22. Consequences of cerebral small vessel
disease: disability, mortality and prognosis Anna Poggesi, Leonardo Pantoni
and Domenico Inzitari; 23. Clinical aspects of genetic forms of small
vessel disease Maria Teresa Dotti and Antonio Federico; 24. Interaction
between cerebral small vessel disease and neurodegenerative changes Wiesje
M. van der Flier and Raj Kalaria; Part IV. Therapeutic Aspects: Prevention,
Future Directions, and Possibilities: 25. Risk factors as possible targets
for prevention of small vessel disease Vincent Mok, Philip B. Gorelick and
Christopher Chen; 26. Treatment approaches for lacunar strokes Makoto
Nakajima, Thalia Field and Oscar R. Benavente; 27. Cerebral small vessels
disease imaging as a surrogate marker for clinical trials Reinhold Schmidt,
Margherita Cavalieri and Marisa Loitfelder; 28. Cerebral small vessel
disease: a look to the future Philip B. Gorelick and Leonardo Pantoni;
Index.