Chemical Biology

Learning through Case Studies
Eds.: Waldmann, Herbert and Janning, Petra

• Broschiertes Buch

Produktbeschreibung

Chemische Biologie - was ist wirklich wichtig? Die Herausgeber dieses Bandes lassen die Praxis selbst die Maßstäbe setzen. Anhand von Fallstudien aus dem Laboralltag, ausgewählt und kommentiert von erfahrenen Autoren, lernt der Leser, bei der Lösung biologischer Probleme die richtigen Prioritäten zu setzen und geeignete Methoden aus der Chemie sinnvoll anzuwenden. Ein motivierendes Buch - nicht nur für Studenten!

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Produktdetails

• Verlag: Wiley-VCH
• 1. Auflage
• Seitenzahl: 271
• Erscheinungstermin: 18. März 2009
• Englisch
• Abmessung: 242mm x 172mm x 16mm
• Gewicht: 600g
• ISBN-13: 9783527323302
• ISBN-10: 3527323309
• Artikelnr.: 25616900

Autorenporträt

Herbert Waldmann received his PhD in 1985 at the University of Mainz under Prof. Kunz in organic chemistry after which he completed a postdoctoral appointment with Prof. G. Whitesides at Harvard University. He was appointed as Professor of Organic Chemistry at the University of Bonn (1991), full Professor of Organic Chemistry at the University of Karlsruhe (1993), and Director at the MPI of Molecular Physiology Dortmund and Professor of Organic Chemistry at the University of Dortmund (1999). His research interests lie in compound libraries, solid-phase synthesis, and Ras proteins.

Petra Janning studied chemistry at the University of Münster (Germany) and did her thesis at the Institute for Analytical Sciences in Dortmund (PhD 1995). After different positions where she worked in the area of analytical chemistry and on the borderline between chemistry and biology she joined the Max Planck Institute of Molecular Physiology, Dortmund in the department of Prof. Dr. H. Waldmann, where she is currently working. She is responsible for the Bioorganic Practical Course and the analytics in the department. She focused her work on the development of chromatographic and mass spectrometric methods used in the institute.

Inhaltsangabe

Foreword
Introduction
Ras Proteins, Synthesis, Ras Cycle
Rab Proteins, Structure, Biochemistry
Proteases, Proteasome
Activity-Based Proteomics
FK506
Regulation of Gene Expression, Transcription
Protein Synthesis, Native Chemcial Ligation
Expressed Protein Ligation
Microarray Technologies
APT1, Ras Palmitoylation
Carbohydrates
Yeast Based Chemical Genomics
Target Identification
BIOS, PSSC, Natural Products
Alzheimer
Diversity Oriented Synthesis
Kinases, Orthogonal Chemical Genetics
Glossary

Rezensionen

"This first book to adopt a problem-based approach teaches the true basics of the subject through illustrated everyday case studies. Each chapter introduces a different biological problem taken from everyday lab work, such that students learn how to solve problems in biology by using techniques and tools taken from chemistry."
METALL (1/2 2010)