High Quality Content by WIKIPEDIA articles! Chemical castration is the administration of medication designed to reduce libido and sexual activity, usually in the hope of preventing rapists, child molesters and other sex offenders from repeating their crimes. Unlike surgical castration, where the testes are removed through an incision in the scrotum, chemical castration does not actually castrate the person, nor is it a form of sterilization, hence the term "chemical castration" has been called a misnomer.