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Bahareh Sadeghi : Faculty member of Islamic Azad University, Central Tehran Branch of Iran. Urmia Lake is located in the north-west of Iran. The salinity of the lake has risen to more than 300 g/L during recent years. The purpose of this present study aims to investigate the relationship between chemical changes, Lake Urmia water-level fluctuation with physical diseases and environment. The results showed that residents around Lake Urmia suffer from lung, eyes, blood pressure, pulmonary, insomnia and respiratory problems. People in regions adjacent to the lake revealed that many were living with respiratory diseases. People should change, not the lake. People who use the water properly and convincing them that the change is good for them. Everyone should learn how much water one uses. situation will change, but not before changing public opinion about using the lake`s water There are probably hundreds of things you are surrounded with that are only given to you by the mercy of Allah. So give thanks and you will make a remarkable change in your life - Alhamdulillah for everything. We persuade people that water is part of the environment, farmers and people will use less water.