Pierfausto Seneci

Chemical Sciences in Early Drug Discovery

Medicinal Chemistry 2.0

• Broschiertes Buch

Produktbeschreibung

Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery.

Produktdetails

• Verlag: Elsevier / Elsevier Science & Technology
• Artikelnr. des Verlages: C2012-0-03607-1
• Seitenzahl: 194
• Englisch
• Abmessung: 9mm x 152mm x 229mm
• Gewicht: 330g
• ISBN-13: 9780080994208
• Artikelnr.: 45636739

Autorenporträt

Pierfausto Seneci has 20 years of medchem experience in both big pharma and start-up private companies, in addition to over a decade of academic experience from the University of Milan, at whose Interdisciplinary Center for Biomolecular Studies and Industrial Applications (CISI) he is currently based. His interests include drug discovery - AB, CNS, oncology -, medchem, high-throughput synthesis, business development in drug discovery, and he has published 80 papers, 1 book on Combichem and 50 international presentations.

Inhaltsangabe

1. Step 1: Target Identification 2. Step II: Target Validation 3. Step IIIa: Biological Hit Discovery Through High-Throughput Screening (HTS): Random Approaches and Rational Design 4. Step IIIb: The Drug-Like Chemical Diversity Pool: Diverse and Targeted Compound Collections