Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Herausgeber: Brahmachari, Goutam

• Gebundenes Buch

Produktbeschreibung

Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure-activity relationships.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 586
• Erscheinungstermin: 20. Februar 2013
• Englisch
• Abmessung: 260mm x 183mm x 36mm
• Gewicht: 1284g
• ISBN-13: 9781439891674
• ISBN-10: 1439891672
• Artikelnr.: 36628159

Autorenporträt

Goutam Brahmachari, Ph.D. is an Associate Professor within the Laboratory of Natural Products and Organic Synthesis, Department of Chemistry, at Visva-Bharati University, India.

Inhaltsangabe

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds.
Impact of Solid-Supported Cyclization-Elimination Strategies toward the
Development of Natural Product Inspired Molecules in Drug Discovery
Research. Synthesis and Biological Studies of Novel ß-Lactams. Applications
of Isatin Chemistry in Organic Synthesis and Medicinal Chemistry. Role of
Organic Carbamates in Anticancer Drug Design. Rational Design of New
Molecules of Biological Significance from Phenolic Constituents of Some
Tropical Plants as Renewable Materials. Synthesis and Biological Activity
of Promising Azole Marine Products: Largazole and Neopeltolide. Omega-3
(¿-3) Polyunsaturated Fatty Acids. Structure and Biological Activity of
Natural Melanin Pigments. Recent Acquisitions on Naturally Occurring
Oxyprenylated Secondary Plant Metabolites. Role of Curcumin in Ameliorating
Neuroinflammation and Neurodegeneration Associated with Alzheimer's
Disease. Plant Metabolites. X-Ray Structural Behavior of Some Significant
Bioactive Steroids and Their Chemistry in the Crystal Packing and Related
Matters. Three-Dimensional Structure of Xanthones. Gambogic Acid.
Neuroplasticity as a New Approach to the Pathophysiology of Depression and
the Role of Antidepressants in Inhibiting Brain Stress-Induced Changes.
Statins. Molecular Aspects of Fungal Bioactive Polyketides. Marine
Microalgal Metabolites. Rosmarinic Acid. Enhancement of Natural
Antioxidants in Plants by Biosynthetic Pathway Modulation. Plant as
Biofactories of Pharmaceuticals and Nutraceuticals.