Chemistry of ¿-(arylhydrazono)-¿-Ketoesters - Gomha, Sobhi M.;Abdelrazek, Fathy M.;Farghaly, Mohamed S.
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The pyrazole nucleus has many biological activities, including several pharmaceuticals currently on the market. Thiazoles are additionally significant class of heterocyclic compounds, found in numerous powerful biologically active drugs such as Ritonavir (antiretroviral drug), Sulfathiazol (antimicrobial drug), Tiazofurin (antineoplastic drug), and Abafungin (antifungal drug). Thiazole derivatives are also known to possess several anticancer activities. Moreover, thiazolyl-pyrazole compounds were identified as as potential anticancer agents. The EGFR PTKs have been identified as interesting…mehr

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Produktbeschreibung
The pyrazole nucleus has many biological activities, including several pharmaceuticals currently on the market. Thiazoles are additionally significant class of heterocyclic compounds, found in numerous powerful biologically active drugs such as Ritonavir (antiretroviral drug), Sulfathiazol (antimicrobial drug), Tiazofurin (antineoplastic drug), and Abafungin (antifungal drug). Thiazole derivatives are also known to possess several anticancer activities. Moreover, thiazolyl-pyrazole compounds were identified as as potential anticancer agents. The EGFR PTKs have been identified as interesting targets for medicinal chemistry programs especially in cancer therapy.
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Autorenporträt
Prof. Sobhi M. Gomha was graduated from Cairo University, Egypt in 1995 then he appointed as a full Professor of Organic chemistry at Cairo University in 2016. Adopting green chemical technologies in heterocyclic synthesis by using Microwave Irradiation, Ultrasonic radiation, and Grinding techniques.