Chemistry of 2-Thiouracil - Awad, Samir
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2-Thiouracil was firstly prepared by Wheeler, Liddle in 1908, then it had been discovered in seeds of Brassica cruciferae in 1941. In 1963, Maloof, Soodak discovered its antithyroid activity which resulted from its interference with the iodination of thyroxine precursors. In 1967 Cardeilhac proved that its mechanism of action as anticancer agent is due to its inhibitory effect on nucleic acid metabolism.

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Produktbeschreibung
2-Thiouracil was firstly prepared by Wheeler, Liddle in 1908, then it had been discovered in seeds of Brassica cruciferae in 1941. In 1963, Maloof, Soodak discovered its antithyroid activity which resulted from its interference with the iodination of thyroxine precursors. In 1967 Cardeilhac proved that its mechanism of action as anticancer agent is due to its inhibitory effect on nucleic acid metabolism.
Autorenporträt
Samir A. Awad, es profesor adjunto y director del Centro de Estudios del Desarrollo de la Universidad de Birzeit, tiene un doctorado en Ciencias Políticas de la Universidad de Columbia, Nueva York. Intereses de investigación: Democracia y democratización, relaciones internacionales de Oriente Medio, construcción del Estado palestino y el proceso de paz.