This textbook builds on the success of the earlier edition, offering alternative strategies for discovering new antibiotics. It discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. It also covers the global action plan on antimicrobial resistance from the World Health Organization and discusses several Antibiotic Stewardship Programs adopted by agencies at local levels.
Appropriate for a one-semester course at either the graduate or advanced undergraduate level, the book is self-contained and written in accessible language. It includes all necessary background biochemistry material and a discussion of the latest developments in the field of antibiotics. Original research works are frequently cited and experimental procedures and interpretation of results are emphasized.
Appropriate for a one-semester course at either the graduate or advanced undergraduate level, the book is self-contained and written in accessible language. It includes all necessary background biochemistry material and a discussion of the latest developments in the field of antibiotics. Original research works are frequently cited and experimental procedures and interpretation of results are emphasized.
"In the Chemistry of Antibiotics and Related Drugs, Bhattacharjee (chemistry and biochemistry, Long Island Univ.) writes about the many different classes of compounds approved over the last century that still are, or have been, used to treat infectious diseases. The book is organized around the targets of these compounds. ... this book is heavily referenced and will be valuable to practicing researchers and advanced students. Summing Up: Recommended. Upper-division undergraduates and above; faculty and professionals." (P. W. Baures, Choice, Vol. 54 (9), May, 2017)