Chemotherapy can be thought of as a way to damage or stress cells, which may then lead to cell death if apoptosis is initiated. Many of the side effects of chemotherapy can be traced to damage to normal cells that divide rapidly and are thus sensitive to anti-mitotic drugs: cells in the bone marrow, digestive tract, and hair follicles. This results in the most common side-effects of chemotherapy myelosuppresion. This book puts spot light on the chemotherapy effect in case of bladder cancer or in urinary system malignant tumor on the bladder function putting spot on using doxyrebocin mitomycin Rubicon in treatment bladder cancer, i used pigs tissues in my experiments as it related to human tissues it would be the basics for clinical trials it detected the effect and side effect of cytotoxic drugs.