An American doctor has his brain transplanted into a Uyghur body in China after an accident in Tibet. He awakes from the surgery as Dr. Wu, who rehabilitates and begins work in China, althoough he still thinks of himself as Roger Scully, MD. After several adventures in China, he returns to the US to restart his career as Scully, but the Colorado medical board accuses him of impersonating a dead person. They have the Chinese death certificate to prove it. The novel ends with him writing a book about chimeras (people with more than one source of DNA). The reader is referred to a website for readers to offer solutions for Scully to regain his identity.
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