This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented.…mehr
This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. Chirality in Industry II * All new case histories * Unique industrial perspective on chiral technology * Emphasis on scale-up and process development * Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches The ?chiral infrastructure? is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of ?chiral chemistry? depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of ?large-scale? thinking. An economic solution is still most likely to be a simple, elegant solution.
Dr. Liam Collins is the executive director of the Madison Policy Forum, a senior fellow with New America, and a permanent member with the Council on Foreign Relations. Colonel (retired) Collins served in the US Army for 27 years. As a career Special Forces officer, he conducted multiple operational and combat deployments to Afghanistan, Iraq, Bosnia, South America, and the Horn of Africa. In Iraq, Liam conducted operations in Baghdad, Fallujah, Ramadi, and many other cities. Liam retired from the military in 2019 as the founding director of the Modern War Institute and the director of the Department of Military Instruction at the United States Military Academy at West Point. He holds a Bachelor of Science degree in Mechanical Engineering (Aerospace) from the United States Military Academy, and a Master's in Public Affairs and a PhD from Princeton University's School of Public and International Affairs.
