Chirality in Industry
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The production of optically active intermediates and products as pure enantiomers is a topic of ever-increasing importance to the chemical industry. The economic incentives of improved cost efficiency and enhanced biological activity, together with new regulatory pressures have, in the last decade, brought about a dramatic increase in the number and scope of industrial processes. Chirality in Industry provides an overview of the production of optically active compounds on a large scale wholly from an industrial perspective. The volume includes example of each of the available process options,…mehr

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Produktbeschreibung
The production of optically active intermediates and products as pure enantiomers is a topic of ever-increasing importance to the chemical industry. The economic incentives of improved cost efficiency and enhanced biological activity, together with new regulatory pressures have, in the last decade, brought about a dramatic increase in the number and scope of industrial processes. Chirality in Industry provides an overview of the production of optically active compounds on a large scale wholly from an industrial perspective. The volume includes example of each of the available process options, from classical resolution procedures to asymmetric syntheses with traditional chemical catalysts and enzyme-based technologies. An extended opening chapter, which systematically considers these options and relates them to a series of important targets, is followed by a series of more detailed case histories by industrial authors summarizing the processes which underpin the large-scale production of several important optically pure intermediates. While Chirality in Industry should prove of particular interest to chemists who are professionally involved in the production of pure enantiomers on a practical scale, it is hoped that students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of "large scale" thinking. An economic solution is more likely to be a simple, elegant solution.
Autorenporträt
Dr. Liam Collins is the executive director of the Madison Policy Forum, a senior fellow with New America, and a permanent member with the Council on Foreign Relations. Colonel (retired) Collins served in the US Army for 27 years. As a career Special Forces officer, he conducted multiple operational and combat deployments to Afghanistan, Iraq, Bosnia, South America, and the Horn of Africa. In Iraq, Liam conducted operations in Baghdad, Fallujah, Ramadi, and many other cities. Liam retired from the military in 2019 as the founding director of the Modern War Institute and the director of the Department of Military Instruction at the United States Military Academy at West Point. He holds a Bachelor of Science degree in Mechanical Engineering (Aerospace) from the United States Military Academy, and a Master's in Public Affairs and a PhD from Princeton University's School of Public and International Affairs.