Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas,…mehr
Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function. Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Part I - History 1. Milestones in the CCK history Jens F. Rehfeld, Christine Feinle-Bisset Part II - Biology of CCK 2. Evolutionarily conserved roles of cholecystokinin signaling Dick Nässel, Shunfan Wu 3. The biogenesis and cell-specific expression of cholecystokinin peptides Jens F. Rehfeld, Christine Feinle-Bisset 4. Cholecystokinin in intestinal and extraintestinal endocrine cells Marta Santoz Hernandez, Frank Reimann, Fiona M. Gribble 5. Cholecystokinin in the central and peripheral nervous system Tomas Hökfelt, Swapnali Barde, Wen Zhong, Jufang He 6. Cholecystokinin 1 and cholecystokinin 2 receptors Laurence J Miller 7. The relationship between cholecystokinin and gastrin Jens F. Rehfeld Part III - Physiology of CCK 8. Intestinal cholecystokinin secretion Rashmi Chandra, Rodger A. Liddle 9. Cholecystokinin and the gut-brain axis Kirsteen Browning, Amanda Page 1. Cholecystokinin and the gallbladder Adrian A. M. Masclee, Gwen M. C. Masclee 11. Cholecystokinin and the exocrine pancreas John A. Williams 12. Islet effects of cholecystokinin and exploitation in diabetes Neil Tanday, Nigel Irwin, Peter Flatt 13. Cholecystokinin and gastrointestinal motor function Javad Anjom Shoae, Michael Horowitz, Christine Feinle-Bisset 14. Effect of cholecystokinin on food intake and appetite Frank A. Duca 15. Cholecystokinin, nutrient preference and taste aversion Jo E. Lewis, Fiona M. Gribble, Frank Reimann 16. Cholecystokinin in peripheral and central cardiovascular control Tony J. M. Verberne, Bashair M. Mussa 17. Cholecystokinin expression in the heart and its clinical implications Jens P. Goetze, Jens F. Rehfeld Part IV - Methods used for CCK research 18. Measurement of cholecystokinin in biological fluids Jens F. Rehfeld, Jens P. Goetze 19. Cholecystokinin knockout mice: peripheral and central phenotypes Chunmin C. Lo, Dennis D. Black, Patrick Tso Part V - CCK in disease 20. Cholecystokinin in obesity and other disorders of eating Kimberly R. Smith, Tim H. Moran 21. Cholecystokinin in tumors Jens F. Rehfeld 22. Cholecystokinin and panic disorder Jacques Bradwejn, Diana Koszycki 23. Cholecystokinin and the immune system John J. Worthington 24. Cholecystokinin and its receptors in nociception and pain Nesia A. Zurek, Sascha R. A. Alles Part V - CCK-based novel therapeutic approaches 25. Potential novel therapeutics targeting cholecystokinin 1 receptors Laurence J. Miller Part VI - Conclusion 26. Reflections on cholecystokinin research - past, present and future Jens F. Rehfeld, Christine Feinle-Bisset
Part I - History 1. Milestones in the CCK history Jens F. Rehfeld, Christine Feinle-Bisset Part II - Biology of CCK 2. Evolutionarily conserved roles of cholecystokinin signaling Dick Nässel, Shunfan Wu 3. The biogenesis and cell-specific expression of cholecystokinin peptides Jens F. Rehfeld, Christine Feinle-Bisset 4. Cholecystokinin in intestinal and extraintestinal endocrine cells Marta Santoz Hernandez, Frank Reimann, Fiona M. Gribble 5. Cholecystokinin in the central and peripheral nervous system Tomas Hökfelt, Swapnali Barde, Wen Zhong, Jufang He 6. Cholecystokinin 1 and cholecystokinin 2 receptors Laurence J Miller 7. The relationship between cholecystokinin and gastrin Jens F. Rehfeld Part III - Physiology of CCK 8. Intestinal cholecystokinin secretion Rashmi Chandra, Rodger A. Liddle 9. Cholecystokinin and the gut-brain axis Kirsteen Browning, Amanda Page 1. Cholecystokinin and the gallbladder Adrian A. M. Masclee, Gwen M. C. Masclee 11. Cholecystokinin and the exocrine pancreas John A. Williams 12. Islet effects of cholecystokinin and exploitation in diabetes Neil Tanday, Nigel Irwin, Peter Flatt 13. Cholecystokinin and gastrointestinal motor function Javad Anjom Shoae, Michael Horowitz, Christine Feinle-Bisset 14. Effect of cholecystokinin on food intake and appetite Frank A. Duca 15. Cholecystokinin, nutrient preference and taste aversion Jo E. Lewis, Fiona M. Gribble, Frank Reimann 16. Cholecystokinin in peripheral and central cardiovascular control Tony J. M. Verberne, Bashair M. Mussa 17. Cholecystokinin expression in the heart and its clinical implications Jens P. Goetze, Jens F. Rehfeld Part IV - Methods used for CCK research 18. Measurement of cholecystokinin in biological fluids Jens F. Rehfeld, Jens P. Goetze 19. Cholecystokinin knockout mice: peripheral and central phenotypes Chunmin C. Lo, Dennis D. Black, Patrick Tso Part V - CCK in disease 20. Cholecystokinin in obesity and other disorders of eating Kimberly R. Smith, Tim H. Moran 21. Cholecystokinin in tumors Jens F. Rehfeld 22. Cholecystokinin and panic disorder Jacques Bradwejn, Diana Koszycki 23. Cholecystokinin and the immune system John J. Worthington 24. Cholecystokinin and its receptors in nociception and pain Nesia A. Zurek, Sascha R. A. Alles Part V - CCK-based novel therapeutic approaches 25. Potential novel therapeutics targeting cholecystokinin 1 receptors Laurence J. Miller Part VI - Conclusion 26. Reflections on cholecystokinin research - past, present and future Jens F. Rehfeld, Christine Feinle-Bisset
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