The objective of this course completion paper was to conduct an in-depth study of the text of Colossians 1.16 through a biblical exegesis, in order to present Jesus Christ as the creator of all things in heaven and on earth, the visible and the invisible. For this, the methodology used was the bibliographic, based on the ideas of other authors who have discussed the subject, as well as through research, investigations in books, internet and mainly through the Holy Scriptures. It was used the text in its original language and in several versions in Portuguese, being carried out manuscriptological, morphological, syntactic and lexicographic analysis of the text. Theological commentaries applicable to daily life were also performed. Finally, it is concluded that the analyzed text reinforces the clear biblical teaching that Jesus Christ is the only Creator of all things that exist in heaven and earth, whether visible or invisible and, therefore, to Him belong all praise and worship.