Children living with disabilities (CWD) are among the most marginalized and excluded in the society. The book aimed at ascertaining the typologies of disabilities among CWD in Malindi Sub-County; challenges faced by CWD, parents and caregivers, how they mitigate them and the role of St. Francis Xavier Roman Catholic Church in addressing the plight of CWD and its efficacy. The study concluded that though the church had put in place some measures in addressing the plight of CWD, the efforts have not been efficient. To achieve efficacy, the study proposed that the church should set up full-fledged disability ministries, involve parents and the entire society in the planning and mainstreaming disability issues and build synergy and proper working relationships with government and other stakeholders.