Chromatin Signaling and Neurological Disorders

Volume 12

• Gebundenes Buch

Produktbeschreibung

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 378
• Erscheinungstermin: 25. Mai 2019
• Englisch
• Abmessung: 236mm x 193mm x 25mm
• Gewicht: 930g
• ISBN-13: 9780128137963
• ISBN-10: 0128137967
• Artikelnr.: 51245922

Inhaltsangabe

1. Chromatin and epigenetic signaling pathways 2. Non-pathologic
neurological development 3. Spinal muscular atrophy 4. Triplet-Repeat
Neurological Diseases 5. Amyotrophic Lateral Sclerosis 6.
Charcot-Marie-Tooth disease 7. Parkinson's disease 8. Huntington's disease
9. Multiple Sclerosis 10. Ataxia Telangiectasia 11. Cockayne Syndrome
neurodevelopmental disorders 12. Angelman Syndrome and Prader-Willi
Syndrome 13. Rett Syndrome 14. Rubinstein-Taybi Syndrome 15. Sotos Syndrome
16. ATRX 17. Fragile X syndrome and mental retardation 18. Autism Spectrum
Disorder and Asperger Syndrome 19. Schizophrenia 20. Gilles de la Tourette
Syndrome 21. Alzheimer's disease (and other dementias) 22. Mood disorders
23. Attention deficit hyperactivity disorder (ADHD) 24. Obsessive
compulsive disorder (OCD)