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Chronic kidney disease is an acute medical and social problem and is a priority of the national health care systems of all industrialised countries of the world. The monograph is devoted to the least studied issue of clinical renal pathophysiology: genetically determined hemostasis pathology in patients with chronic kidney disease. The work briefly summarizes the fundamental and recent literature data concerning the medico-social significance and key mechanisms of chronic kidney disease progression, and also presents the authors' views on the indicated problem, formed on the basis of their own…mehr

Produktbeschreibung
Chronic kidney disease is an acute medical and social problem and is a priority of the national health care systems of all industrialised countries of the world. The monograph is devoted to the least studied issue of clinical renal pathophysiology: genetically determined hemostasis pathology in patients with chronic kidney disease. The work briefly summarizes the fundamental and recent literature data concerning the medico-social significance and key mechanisms of chronic kidney disease progression, and also presents the authors' views on the indicated problem, formed on the basis of their own research results. The results of study of prevalence, clinical and prognostic significance of polymorphism of II, V clotting factors and methylentetrahydrofolate reductase genes in patients with chronic glomerulonephritis and diabetic nephropathy are presented and discussed. The monograph is intended for pathophysiologists, laboratory physicians, nephrologists, hematologists and doctors of other specialties, as well as will be useful for students of medical universities, interns, clinical residents and graduate students.
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Autorenporträt
Vadim V. Kalyuzhin, profesor del Departamento de Terapia Hospitalaria de la Universidad Médica Estatal de Siberia, Ministerio de Salud y Desarrollo Social de Rusia. Sibireva Olga Filippovna, Jefa del Laboratorio Clínico, Hospital Clínico Regional de Tomsk. Kalyuzhina Elena Viktorovna, profesora del Departamento de Terapia de la Universidad Médica Estatal de Siberia, Ministerio de Sanidad y Desarrollo Social de Rusia.