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While there have been many recent books on the cell surface and a few on the topic of cilia and flagella, this is the fIrst volume that attempts to bring together the available informa tion on ciliary and flagellar membranes. This reflects a slow awakening by cell biologists and other scientists to the signifIcance of ciliary and flagellar surfaces. When Michael Sleigh edited an excellent book entitled Cilia and Flagella in 1974, not one of the sixteen chapters was devoted to ciliary or flagellar surfaces. When W. B. Amos and J. G. Duckett edited the very fIne 25th Symposium of the Society…mehr
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While there have been many recent books on the cell surface and a few on the topic of cilia and flagella, this is the fIrst volume that attempts to bring together the available informa tion on ciliary and flagellar membranes. This reflects a slow awakening by cell biologists and other scientists to the signifIcance of ciliary and flagellar surfaces. When Michael Sleigh edited an excellent book entitled Cilia and Flagella in 1974, not one of the sixteen chapters was devoted to ciliary or flagellar surfaces. When W. B. Amos and J. G. Duckett edited the very fIne 25th Symposium of the Society for Experimental Biology on Prokaryotic and Eukaryotic Flagella in 1982, only two of the twenty chapters on eu karyotic cilia and flagella were devoted to ciliary and flagellar surfaces. Only in 1989 has the timing become right to produce a volume entirely devoted to the nonaxonemal struc tures and functions of eukaryotic cilia and flagella. The fIfteen chapters in this volume cover a wide spectrum of organisms (from protozoa and algae to birds and mammals) and an equally wide spectrum of topics (from sexual interactions in the algae to the binding of pathogens in the lung).
Produktdetails
- Produktdetails
- Verlag: Springer, Berlin
- 1990.
- Seitenzahl: 450
- Erscheinungstermin: Januar 1990
- Englisch
- Gewicht: 1180g
- ISBN-13: 9780306432798
- ISBN-10: 030643279X
- Artikelnr.: 26052886
- Verlag: Springer, Berlin
- 1990.
- Seitenzahl: 450
- Erscheinungstermin: Januar 1990
- Englisch
- Gewicht: 1180g
- ISBN-13: 9780306432798
- ISBN-10: 030643279X
- Artikelnr.: 26052886
1. Introduction to Cilia and Flagella.- 1. Introduction.- 2. Occurrence and Function.- 3. Structure.- 3.1. The Axoneme.- 3.2. The Transition Zone.- 3.3. The Basal Body and Associated Structures.- 3.4. Accessory Structures of the Flagellar Shaft.- 4. Production of Movement.- 4.1. The Sliding Microtubule Model.- 4.2. Active Sliding Is Produced by Dynein Arms Acting on Adjacent Outer Doublet Microtubules.- 4.3. The Mechanism of Force Generation.- 4.4. Internal Resistances Convert Sliding into Bending.- 4.5. Coordination of Interdoublet Sliding.- 4.6. Central Pair Rotation.- 5. Regulation of Movement.- 5.1. Initiation of Motility.- 5.2. Behavioral Responses.- 5.3. Hyperactivation of Sperm.- 6. Sensory Reception.- 7. Origin.- References.- 2. Linkages between Microtubules and Membranes in Cilia and Flagella.- 1. Introduction.- 2. Linkage of Basal Bodies and Transition Regions to the Membrane.- 2.1. Structural Studies.- 2.2. Functions of the Bridges.- 3. Microtubule Capping Structures Attach the Ends of Microtubules to the Membrane.- 3.1. Capping Structures and Motility.- 3.2. Capping Structures and Microtubule Assembly.- 3.3. Caps Are Bound to Assembling and Disassembling Microtubules.- 3.4. Can Capping Structures Regulate Tubulin Addition to Microtubules?.- 3.5. Are Microtubule Caps Found in the Cytoplasm?.- 4. Bridges Linking the Sides of Outer Doublet Microtubules to the Membrane.- 4.1. Bridges Linking Microtubules to Extraciliary Structures.- 4.2. Sites of Attachment of the Bridges.- 4.3. Attachment to the Doublet Microtubules.- 4.4. Sites of Membrane Attachment.- 4.5. Nonciliary Microtubule-Membrane Bridges.- 4.6. Functions of the Bridges.- 5. Summary.- References.- 3. Euglena gracilis: A Model for Flagellar Surface Assembly, with Reference to Other Cells That Bear Flagellar Mastigonemes and Scales.- 1. Introduction.- 2. The Relationship of Euglenoids to Other Organisms.- 3. Flagellar Anatomy.- 3.1. Mastigonemes and the Flagellar Sheath.- 3.2. The Paraxial Rod.- 3.3. The Flagellar Membrane.- 4. Assembly of the Flagellar Surface.- 4.1. Origin of Flagellar Scales, Mastigonemes, and Membranes.- 4.2. Composition of Scales and Mastigonemes.- 4.3. Release of Mastigonemes and Flagellar Scales at the Cell Surface.- 4.4. Organizing the Flagellar Surface.- 5. The Control of Flagellar Surface Assembly in Euglena.- 6. Summary and Prospectus.- References.- 4. Gliding Motility and Flagellar Glycoprotein Dynamics in Chlamydomonas.- 1. Introduction.- 2. Gliding Motility.- 2.1. Gliding Motility-An Overview.- 2.2. Gliding Motility in Chlamydomonas.- 3. Polystyrene Microsphere Movements.- 4. Flagellar Surface Motility.- 5. Mating-Associated Dynamic Flagellar Surface Events.- 6. Characterization of the Major Flagellar Glycoproteins in C. reinhardtii.- 7. Dynamics of Flagellar Membrane Glycoproteins.- 8. Flagellar Signaling in Chlamydomonas.- 8.1. Signaling Related to Gametic Interactions.- 8.2. Signaling Related to Glycoprotein Redistribution in Vegetative Flagella.- 9. Use of Carbohydrate Probes in Conjunction with FACS to Isolate Mutant Cell Lines with Carbohydrate Defects.- 10. Use of the L-23 Mutant Cell Line to Demonstrate That Flagellar Membrane Glycoprotein Movements Are Essential for Gliding Motility.- 11. Mechanisms and Motors.- 11.1. Candidates for the Motor Responsible for Flagellar Membrane Protein Redistribution and Gliding Motility.- 11.2. A Proposed Mechanism for Gliding Motility.- 12. Conclusions.- References.- 5. The Role of Flagella in the Sexual Reproduction of Chlamydomonas Gametes.- 1. Introduction.- 2. The Agglutination Process.- 3. The Agglutinins.- 4. Mode of Action of the Agglutinins.- 5. Longitudinal Redistribution of Agglutinins.- 6. The Signaling Action of Sexual Agglutination.- 7. Modulation of Sexual Agglutinability.- 8. Conclusions.- References.- 6. The Role of Ciliary Surfaces in Mating in Paramecium.- 1. Introduction.- 2. The Events Occurring during Conjugation in Paramecium.- 3. Role of Ciliary Surfaces in the
1. Introduction to Cilia and Flagella.- 1. Introduction.- 2. Occurrence and Function.- 3. Structure.- 3.1. The Axoneme.- 3.2. The Transition Zone.- 3.3. The Basal Body and Associated Structures.- 3.4. Accessory Structures of the Flagellar Shaft.- 4. Production of Movement.- 4.1. The Sliding Microtubule Model.- 4.2. Active Sliding Is Produced by Dynein Arms Acting on Adjacent Outer Doublet Microtubules.- 4.3. The Mechanism of Force Generation.- 4.4. Internal Resistances Convert Sliding into Bending.- 4.5. Coordination of Interdoublet Sliding.- 4.6. Central Pair Rotation.- 5. Regulation of Movement.- 5.1. Initiation of Motility.- 5.2. Behavioral Responses.- 5.3. Hyperactivation of Sperm.- 6. Sensory Reception.- 7. Origin.- References.- 2. Linkages between Microtubules and Membranes in Cilia and Flagella.- 1. Introduction.- 2. Linkage of Basal Bodies and Transition Regions to the Membrane.- 2.1. Structural Studies.- 2.2. Functions of the Bridges.- 3. Microtubule Capping Structures Attach the Ends of Microtubules to the Membrane.- 3.1. Capping Structures and Motility.- 3.2. Capping Structures and Microtubule Assembly.- 3.3. Caps Are Bound to Assembling and Disassembling Microtubules.- 3.4. Can Capping Structures Regulate Tubulin Addition to Microtubules?.- 3.5. Are Microtubule Caps Found in the Cytoplasm?.- 4. Bridges Linking the Sides of Outer Doublet Microtubules to the Membrane.- 4.1. Bridges Linking Microtubules to Extraciliary Structures.- 4.2. Sites of Attachment of the Bridges.- 4.3. Attachment to the Doublet Microtubules.- 4.4. Sites of Membrane Attachment.- 4.5. Nonciliary Microtubule-Membrane Bridges.- 4.6. Functions of the Bridges.- 5. Summary.- References.- 3. Euglena gracilis: A Model for Flagellar Surface Assembly, with Reference to Other Cells That Bear Flagellar Mastigonemes and Scales.- 1. Introduction.- 2. The Relationship of Euglenoids to Other Organisms.- 3. Flagellar Anatomy.- 3.1. Mastigonemes and the Flagellar Sheath.- 3.2. The Paraxial Rod.- 3.3. The Flagellar Membrane.- 4. Assembly of the Flagellar Surface.- 4.1. Origin of Flagellar Scales, Mastigonemes, and Membranes.- 4.2. Composition of Scales and Mastigonemes.- 4.3. Release of Mastigonemes and Flagellar Scales at the Cell Surface.- 4.4. Organizing the Flagellar Surface.- 5. The Control of Flagellar Surface Assembly in Euglena.- 6. Summary and Prospectus.- References.- 4. Gliding Motility and Flagellar Glycoprotein Dynamics in Chlamydomonas.- 1. Introduction.- 2. Gliding Motility.- 2.1. Gliding Motility-An Overview.- 2.2. Gliding Motility in Chlamydomonas.- 3. Polystyrene Microsphere Movements.- 4. Flagellar Surface Motility.- 5. Mating-Associated Dynamic Flagellar Surface Events.- 6. Characterization of the Major Flagellar Glycoproteins in C. reinhardtii.- 7. Dynamics of Flagellar Membrane Glycoproteins.- 8. Flagellar Signaling in Chlamydomonas.- 8.1. Signaling Related to Gametic Interactions.- 8.2. Signaling Related to Glycoprotein Redistribution in Vegetative Flagella.- 9. Use of Carbohydrate Probes in Conjunction with FACS to Isolate Mutant Cell Lines with Carbohydrate Defects.- 10. Use of the L-23 Mutant Cell Line to Demonstrate That Flagellar Membrane Glycoprotein Movements Are Essential for Gliding Motility.- 11. Mechanisms and Motors.- 11.1. Candidates for the Motor Responsible for Flagellar Membrane Protein Redistribution and Gliding Motility.- 11.2. A Proposed Mechanism for Gliding Motility.- 12. Conclusions.- References.- 5. The Role of Flagella in the Sexual Reproduction of Chlamydomonas Gametes.- 1. Introduction.- 2. The Agglutination Process.- 3. The Agglutinins.- 4. Mode of Action of the Agglutinins.- 5. Longitudinal Redistribution of Agglutinins.- 6. The Signaling Action of Sexual Agglutination.- 7. Modulation of Sexual Agglutinability.- 8. Conclusions.- References.- 6. The Role of Ciliary Surfaces in Mating in Paramecium.- 1. Introduction.- 2. The Events Occurring during Conjugation in Paramecium.- 3. Role of Ciliary Surfaces in the