Unter Zirkulardichroismus (CD) versteht man die spezifisch unterschiedliche Absorption von links- und rechtszirkular polarisiertem Licht durch bestimmte Moleküle. CD-Effekte lassen sich in Abhängigkeit von der Wellenlänge messen und spektroskopisch auswerten. Dieser Band erläutert Theorie und Anwendung der CD-Spektroskopie insbesondere für Biomoleküle. Ausführlich behandelt werden Anwendungen auf den Gebieten der organischen Stereochemie und der Biopolymere. Geschrieben von anerkannten Spezialisten! (06/00)
Unter Zirkulardichroismus (CD) versteht man die spezifisch unterschiedliche Absorption von links- und rechtszirkular polarisiertem Licht durch bestimmte Moleküle. CD-Effekte lassen sich in Abhängigkeit von der Wellenlänge messen und spektroskopisch auswerten. Dieser Band erläutert Theorie und Anwendung der CD-Spektroskopie insbesondere für Biomoleküle. Ausführlich behandelt werden Anwendungen auf den Gebieten der organischen Stereochemie und der Biopolymere. Geschrieben von anerkannten Spezialisten! (06/00)
NINA BEROVA, PhD, is a Professor and Senior Research Scientist in the Department of Chemistry at Columbia University, New York. She is the North American Editor of the international journal Chirality. KOJI NAKANISHI, PhD, is Centennial Professor of Chemistry in the Department of Chemistry at Columbia University, New York. He is the recipient of many international awards and the Person of Cultural Merit Award (Japanese government). ROBERT W. WOODY, PhD, is a Professor in the Department of Biochemistry and Molecular Biology at Colorado State University, Fort Co
Inhaltsangabe
PARTIAL TABLE OF CONTENTS: Circular Dichroism: An Introduction (G. Snatzke). From Pasteur to Parity Nonconservation: Theories of the Origin of Molecular Chirality (S. Mason). Theoretical Approach to Electronic Optical Activity (A. Koslowski, et al.). Vibrational Optical Acivity Theory (L. Nafie & T. Freedman). Fast Time-Resolved Circular Dichroism Measurements (D. Kliger & J. Lewis). The Octant Rule (D. Lightner). Circular Dichroism and Chirality of Dienes (J. Gawroski). Exciton Chirality Method: Principles and Applications (N. Berova & K. Nakanishi). A Model for How Polymers Amplify Chirality (M. Green). Induced CD or Polymers (E. Yashima & Y. Okamoto). Application of CD to the Study of Some Cholesteric Mesophase (G. Gottarelli & G. Spada). Circular Dichroism of Inorganic Complexes: Interpretation and Applications (R. Kuroda). Circular Dichroism of Peptides and Proteins (N. Sreerama & R. Woody). Peptide and Protein Conformational Studies with Vibrational Circular Dichroism and Related Spectroscopies (T. Keiderling). HPLC-CD: Stereochemical Analysis at Work (P. Salvadori, et al.). Applications of Chiroptical Spectroscopy in the Characterization of Compounds Having Pharmaceutical Importance (H. Brittain). Index.
PARTIAL TABLE OF CONTENTS: Circular Dichroism: An Introduction (G. Snatzke). From Pasteur to Parity Nonconservation: Theories of the Origin of Molecular Chirality (S. Mason). Theoretical Approach to Electronic Optical Activity (A. Koslowski, et al.). Vibrational Optical Acivity Theory (L. Nafie & T. Freedman). Fast Time-Resolved Circular Dichroism Measurements (D. Kliger & J. Lewis). The Octant Rule (D. Lightner). Circular Dichroism and Chirality of Dienes (J. Gawroski). Exciton Chirality Method: Principles and Applications (N. Berova & K. Nakanishi). A Model for How Polymers Amplify Chirality (M. Green). Induced CD or Polymers (E. Yashima & Y. Okamoto). Application of CD to the Study of Some Cholesteric Mesophase (G. Gottarelli & G. Spada). Circular Dichroism of Inorganic Complexes: Interpretation and Applications (R. Kuroda). Circular Dichroism of Peptides and Proteins (N. Sreerama & R. Woody). Peptide and Protein Conformational Studies with Vibrational Circular Dichroism and Related Spectroscopies (T. Keiderling). HPLC-CD: Stereochemical Analysis at Work (P. Salvadori, et al.). Applications of Chiroptical Spectroscopy in the Characterization of Compounds Having Pharmaceutical Importance (H. Brittain). Index.
Rezensionen
"Reviews historical developments and recent advances in the field of circular dichroism, bridging the gap between theory and practice." (SciTech Book News, Vol. 24, No. 4, December 2000) "I wholeheartedly recommend this book to all who are interested in chirality. For medicinal and synthetic chemists working with chiral substances...this is a very useful reference book." (Journal of Medicinal Chemistry, Vol. 44, No. 7, 2001) "...this book will make a valuable addition to the libraries of the cognoscenti..." (Analytical Biochemistry, Vol. 294, 2001) "...this book serves as an excellent resource for information regarding circular dichroism." (Pharmaceutical Research, Vol. 18, No. 4, April 2001) "This excellent book provides the reader with a snapshot of contemporary research on CD and related topics. It should be of great value to a wide variety of chemists and biochemists." (Journal of the American Chemical Society, Vol. 124, 2002)
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