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Today,hyperactivity or attention deficit disorder in children,neurological disorders are incurable and usually fatal disease. Hyperactivity always caused by genetic mutations that have the potential to be transmitted from mother to child.If the mother during pregnancy, uses the drug as well as strong antibiotics and sedatives as well as taking abortion drugs,the probability that a child is hyperactive increases.In this study we have analyzed 1200 children. 580 children with ADHD and 620 children in control group. The genes DSM-IV, DRD4, SERT, HTR1B, SNAP25, GRIN2A, ADRA2A, TPH2 and BDNF were analyzed in terms of genetic mutations made. In this study, children who have genetic mutations were targeted, with nervous disorders, ADHD. In fact, all children with ADHD, 360 children had a genetic mutation in the genes DSM-IV, DRD4, SERT, HTR1B. And 100 children had a genetic mutations in SNAP25, GRIN2A genes were a genetic mutations in the genes ADRA2A, TPH2 and BDNF and 70 children, respectively. Any genetic mutations in the target genes control group, were not shown.