Classics in Stereoselective Synthesis - Carreira, Erick M.; Kvaerno, Lisbet
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This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of stereochemically complex structures.
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Produktbeschreibung
This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of stereochemically complex structures.

From the contents:

"Macrocyclic stereocontrol
"Carbonyl addition reactions
"alpha-Functionalization of enolates
"Aldol and allylation reactions
"Chiral acetals
"Alkene hydroboration, reduction, and oxidation
"Additions to C=N bonds and synthesis of amino acids
"Conjugate additions
"Chiral carbanions
"Metal-catalyzed allylations
"Cyclopropanations and CH-insertion reactions
"Sigmatropic rearrangements
"Diels-Alder and hetero-Diels-Alder reactions
"[3+2]- and [2+2]-cycloaddition reactions
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Autorenporträt
Professor Carreira obtained his Ph.D. degree in 1990 from Harvard University and became Assistant Professor at the same faculty in 1992. After becoming full professor in 1997 he moved to ETH Zürich in 1998. He is recipient of many awards among them the Nobel Laureate Signature Award and the ACS Award in Pure Chemistry. His research focuses on asymmetric synthesis of natural products.

Professor Woerpel´s research focuses on the development of new methods for organic synthesis and emphasizes the stereoselective carbon-carbon bond formation reactions. He is the recipient of many awards, among them th Camille Dreyfus Teacher-Scholar Award and the Astra Zeneca Excellence in Chemistry Award.

Professor Reiser obtained his Ph.D. in 1989 from the University of Hamburg. After becoming Professor in Göttingen 1995 he worked on stereoselective snytheses and catalysis under high pressure.