Clearance (medicine)
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In medicine, the clearance is a measurement of the renal excretion ability. Although clearance may also involve other organs than the kidney, it is almost synonymous with renal clearance or renal plasma clearance. Each substance has a specific clearance that depends on its filtration characteristics. Clearance is a function of glomerular filtration, secretion from the peritubular capillaries to the nephron, and reabsorption from the nephron back to the peritubular…mehr

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In medicine, the clearance is a measurement of the renal excretion ability. Although clearance may also involve other organs than the kidney, it is almost synonymous with renal clearance or renal plasma clearance. Each substance has a specific clearance that depends on its filtration characteristics. Clearance is a function of glomerular filtration, secretion from the peritubular capillaries to the nephron, and reabsorption from the nephron back to the peritubular capillaries. Clearance is constant in first-order kinetics because a constant fraction of the drug is eliminated per unit time, but it is variable in zero-order kinetics, because a constant amount of drug is eliminated per unit time.