Cleft lip and/or cleft palate in a Sub-Saharan Africa region - Mbuyi Musanzayi, Sébastien
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Cleft lip and/or cleft palate is a frequent congenital malformation which causes a major burden to the patient, his family and to society. The extensive scientific literature on diverse aspects of CL/P stands in sharp contrast with the limited knowledge on this subject in Sub-Saharan countries, including the DR Congo. Therefore, we initiated a scientific study in Lubumbashi, on the epidemiology, the environmental and genetic factors involved and the outome after surgery for CL/P. We reported an incidence of 0.84/1000 live births. A multifactorial cause is most common, with an interaction of…mehr

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Produktbeschreibung
Cleft lip and/or cleft palate is a frequent congenital malformation which causes a major burden to the patient, his family and to society. The extensive scientific literature on diverse aspects of CL/P stands in sharp contrast with the limited knowledge on this subject in Sub-Saharan countries, including the DR Congo. Therefore, we initiated a scientific study in Lubumbashi, on the epidemiology, the environmental and genetic factors involved and the outome after surgery for CL/P. We reported an incidence of 0.84/1000 live births. A multifactorial cause is most common, with an interaction of multiple genetic and environmental factors such as maternal alcohol intake during pregnancy, maternal educational level lower than high school, clay (Pemba) consumption, the use of insecticides in the evening, indoor cooking with charcoal (Makala), and regular consumption of Kapolowe fish, supposedly contaminated with heavy metals. Clinical genetic evaluation and genetic testing have an increasing role in the evaluation of patients with clefting. Adequate surgical repair of cleft lip and/or cleft palate (CL/P) is key to improving the anatomical and functional aspects of these structures.
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Autorenporträt
Mr. MBUYI MUSANZAYI Sébastien was born in Lubumbashi on January 3, 1981 at Maman Mobutu Hospital. He completed his university studies in Medicine at the University of Lubumbashi. He has a full master's degree in general surgery and he is certified in pediatric and maxillofacial surgery. He is Professor (PhD) at the University of Lubumbashi.