Toxoplasmosis is a protozoan infection that has a cosmopolitan distribution and has also been documented as the commonest opportunistic infection affecting the central nervous system among patients with HIV/AIDS in developed countries, especially among those not taking appropriate prophylactic treatment. Although the human infection is usually asymptomatic or mild, the disease entity is life-threatening among immune-compromised patients, who frequently develop cerebral toxoplasmosis along with other associated opportunistic infections that are typically seen among HIV/AIDS patients. Healthcare teachers deployed to work in busy healthcare institutions and learners under their instruction require quick reference material to guide in diagnosis and management of toxoplasmosis. This book therefore provides the summarized essential details to enable the readers save on time while searching for relevant information required for pathophysiology, clinical presentation, complications, diagnosis and management of toxoplasmosis.