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As a new infectious disease that carries a high risk of admission to the intensive care unit, it is particularly important to explore the clinical characteristics of COVID-19, which may help to adequately manage its sequelae in the post-acute phase. Objective: To describe the clinical, tomographic characteristics, respiratory function and laboratory tests of patients diagnosed with SARS-CoV-2 at El Pilar Medical Center and Hospital in Guatemala during June 2020 to March 2021. Material and methods: Retrospective descriptive study of patients admitted to the respiratory area service at the El Pilar Medical Center and Hospital of Guatemala with a diagnosis of Sars-CoV-2 during the months of June 2020 to March 2021.