Clinical Neuroendocrinology , a volume in the Handbook of Clinical Neurology Series gives an overview of the current knowledge in the field of clinical neuroendocrinology. It focuses on the pathophysiology, diagnosis, and treatment of diseases of the hypothalamus and the pituitary gland. It integrates a large number of medical disciplines, including clinical endocrinology, pediatrics, neurosurgery, neuroradiology, clinical genetics, and radiotherapy. Psychological consequences of various disorders and therapies, as well as therapeutic controversies, are discussed. It is the first textbook in…mehr
Clinical Neuroendocrinology, a volume in the Handbook of Clinical Neurology Series gives an overview of the current knowledge in the field of clinical neuroendocrinology. It focuses on the pathophysiology, diagnosis, and treatment of diseases of the hypothalamus and the pituitary gland. It integrates a large number of medical disciplines, including clinical endocrinology, pediatrics, neurosurgery, neuroradiology, clinical genetics, and radiotherapy. Psychological consequences of various disorders and therapies, as well as therapeutic controversies, are discussed. It is the first textbook in the field to address all these aspects by a range of international experts.
Eric Fliers is Professor of Endocrinology at the University of Amsterdam, serving as head of the Department of Endocrinology and Metabolism at the Academic Medical Center in Amsterdam since 2007. He received a PhD in Neuroscience on the functional neuroanatomy of the human hypothalamus, followed by his MD (with honors), both from the University of Amsterdam. He was subsequently trained as an internist-endocrinologist. Fliers was one of the founders of the Netherlands Brain Bank. His current research interests include the hypothalamus-pituitary-thyroid axis, and the neuro-endocrine response to illness. Eric Fliers is the current chair of the Dutch Endocrine Society.
Inhaltsangabe
Section 1 Clinical aspects of hypothalamic function Development 1. Genetic aspects of hypothalamic and pituitary gland development 2. Neuroendocrinology of pregnancy and parturition Vasopressin, oxytocin, CRH 3. Disorders of water metabolism: diabetes insipidus and the syndrome of inappropriate antidiuretic hormone secretion 4. Oxytocin and vasopressin's role in emotional and social behaviors 5. Corticotrophin-releasing hormone and the hypothalamic-pituitary-adrenal axis in psychiatric disease Metabolism 6. Genetic aspects of human obesity 7. Sleep characteristics and insulin sensitivity in humans 8. Hypothalamic neuropeptides in critical illness 9. Central regulation of the hypothalamo-pituitary-thyroid (HPT) axis - focus on clinical aspects
Section 2 Disorders of the pituitary gland Diagnostic approach 10. Evaluation of pituitary function 11. Imaging of pituitary pathology Pituitary pathologies 12. Non-functioning pituitary tumors 13. Hyperprolactinemia and prolactinoma 14. Acromegaly 15. Cushing's disease 16. Craniopharyngioma 17. Rathke's cleft 18. Alternative causes of hypopituitarism: traumatic brain injury, cranial irradiation and infections Therapeutic approach to pituitary tumors 19. Surgical approach to pituitary tumors 20. Medical approach to pituitary tumors 21. Radiation therapy in the management of pituitary adenomas
Section 3 Controversial issues and hot topics 22. Nelson Syndrome, definition and management 23. Familial pituitary tumours 24. Long-term effects of treatment of pituitary adenomas 25. Neuroendocrine mechanisms in athletes 26. Uncertainties in endocrine substitution therapy for central hypocortisolism 27. Uncertanties in endocrine substitution therapy for central endocrine insufficiencies: Hypothyroidism 28. Uncertanties in endocrine substitution therapy for central endocrine insufficiencies: growth hormone deficiency 29. Autoimmune hypophysitis: new developments
Section 1 Clinical aspects of hypothalamic function Development 1. Genetic aspects of hypothalamic and pituitary gland development 2. Neuroendocrinology of pregnancy and parturition Vasopressin, oxytocin, CRH 3. Disorders of water metabolism: diabetes insipidus and the syndrome of inappropriate antidiuretic hormone secretion 4. Oxytocin and vasopressin's role in emotional and social behaviors 5. Corticotrophin-releasing hormone and the hypothalamic-pituitary-adrenal axis in psychiatric disease Metabolism 6. Genetic aspects of human obesity 7. Sleep characteristics and insulin sensitivity in humans 8. Hypothalamic neuropeptides in critical illness 9. Central regulation of the hypothalamo-pituitary-thyroid (HPT) axis - focus on clinical aspects
Section 2 Disorders of the pituitary gland Diagnostic approach 10. Evaluation of pituitary function 11. Imaging of pituitary pathology Pituitary pathologies 12. Non-functioning pituitary tumors 13. Hyperprolactinemia and prolactinoma 14. Acromegaly 15. Cushing's disease 16. Craniopharyngioma 17. Rathke's cleft 18. Alternative causes of hypopituitarism: traumatic brain injury, cranial irradiation and infections Therapeutic approach to pituitary tumors 19. Surgical approach to pituitary tumors 20. Medical approach to pituitary tumors 21. Radiation therapy in the management of pituitary adenomas
Section 3 Controversial issues and hot topics 22. Nelson Syndrome, definition and management 23. Familial pituitary tumours 24. Long-term effects of treatment of pituitary adenomas 25. Neuroendocrine mechanisms in athletes 26. Uncertainties in endocrine substitution therapy for central hypocortisolism 27. Uncertanties in endocrine substitution therapy for central endocrine insufficiencies: Hypothyroidism 28. Uncertanties in endocrine substitution therapy for central endocrine insufficiencies: growth hormone deficiency 29. Autoimmune hypophysitis: new developments
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