HIV/AIDS is a global pandemic which affects all body parts including the eyes. Ocular lesions are varied and affect almost all parts of the eye. HIV-related ocular complications may result into visual impairment and even blindness which affects the quality of life of the patients. This was a cross-sectional study done at Mbarara Regional Referral Hospital Immune Suppression syndrome (MRRH/ISS) clinic. Systematic random sampling was used to get participants who were 18 years. Participants' demographic data and medical history including the most recent CD4-count were recorded. Distance visual acuity for each participant was determined. The lids, anterior and posterior segments of the eyes were examined for any lesions. Objective and subjective refraction including near vision was done. Visual impairment was defined as presenting visual acuity that is worse than 6/18, in the better eye, with presenting optical correction, if any. Data were collected using standard optometric instruments and a questionnaire. Data were entered and analyzed using Microsoft Excel software packages and STATA version 12.0.