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This book discusses the connection between oral health and systemic diseases. It describes how to manage medically compromised patients for periodontal treatment and several important factors to be considered. Most medically compromised patient seeks oral health care. An understanding of a compromised state is necessary as it may lead to complications and requires specialists to consult before any treatment or advising any drugs. The purpose of this book is to give a brief management protocol for medically compromised patients in periodontics and also enables the reader to recognize and give proper treatment to patients with various medical problems.