Breast pathology is a frequent reason for women's consultation and still remains a major public health problem. Its management requires a well-coded diagnostic and therapeutic arsenal. The clinic, mammography and ultrasound are the main methods of breast diagnosis, hence the need to verify the respective values of each method by comparing them with the final histological results. For this reason, this retrospective study of 250 cases was carried out. The results of the clinical-radiological-histological combination are much better than those obtained for each method separately.