Fatai Adewale Fehintola

Clinical trial of chloroquine-chorpheniramine in malaria

Clinical trial of antimalarial drugs

• Broschiertes Buch

Produktbeschreibung

This book reported the study on efficacy and safety of chloroquine-chlorpheniramine and halofantrine in malaria paediatric patient. 88 children with acute symptomatic uncomplicated malaria were randomised to receive chloroquine-chlorpheniramine (45) or halofantrine (43). All the children were monitored daily (clinical and parasitological examinations) for 8 days then weekly for 2 weeks.Fever and other symptoms cleared faster in halofantrine group within 8 days. The malaria parasites also cleared faster in children that received halofantrine when compared with chloroquine-chlorpheniramine group within 8 days.However there was no significant difference between chloroquine-chlorpheniramine and halofantrine groups in both symptoms and parasite clearance at 14th day. Halofantrine group had intravascular haemolysis and abdominal pain with or without vomiting while chloroquine-chlorpheniramine group had pruritus as major side effects.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 88
• Erscheinungstermin: 8. Juli 2013
• Englisch
• Abmessung: 220mm x 150mm x 6mm
• Gewicht: 150g
• ISBN-13: 9783659415555
• ISBN-10: 3659415553
• Artikelnr.: 39058871

Autorenporträt

FA Fehintola holds MBBS(1989)&MSc Pharmacology(1999) degrees ofUniversity of Ibadan.He is a fellow of National Postgraduate Medical College,Nigeria (Clinical Pharmacology)2000. He had been a Lecturer(1999)& Consultant Clinical Pharmacologist(2001) to University of Ibadan&University College Hospital& published tens of articles in reputable journals