Suchetan P. A., Naveen S.

Cocrystals of Sulfa Drugs

Structures toApplications

• Broschiertes Buch

Produktbeschreibung

Sulfa drugs are highly effective antimicrobial agents against bacterial infections. However, they lose their spot in the market against other commercially available drugs owing to their either low solubility and/or permeability. They are either class II or class IV drugs in BCS classification, and therefore, have to be consumed in larger doses for effective medication. Consuming drugs in larger dose may lead to complexities/adverse effects (which are summarized in the introduction), and is also not an ideal business strategy. Though sulfa drugs are replaced in the pharmaceutical market by other active pharmaceutical ingredients (APIs), they are still useful because of their low cost and efficient action against common bacterial diseases. Therefore, addressing their solubility and permeability issues are still valid. One of the strategies that is generally used to improve the solubility of APIs is by using crystal engineering principles, wherein, solid forms of APIs are formulatedas cocrystals with different bio-acceptable coformers.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 112
• Erscheinungstermin: 30. November 2024
• Englisch
• Abmessung: 220mm x 150mm x 7mm
• Gewicht: 185g
• ISBN-13: 9786208170516
• ISBN-10: 6208170516
• Artikelnr.: 72655747

Autorenporträt

Dr. Suchetan P. A. is currently serving as Associate Professor of Chemistry at University College of Science, Tumkur University, India. He has teaching and research experience of 15 years, and has served the University and College administration at different positions such as Deputy Registrar of Academics, examinations and Special Officer.