Our prospective descriptive study on the management of diarrhea by mothers of children under 5 years of age in the village of Zaguinasso/Kouto revealed that mothers have a good knowledge of diarrhea, especially of the signs of severity of this condition, and that they generally have good habits for managing diarrhea. Nevertheless, given the seriousness and frequency of diarrhea among our children in our regions, we must find effective strategies to reduce the incidence of this condition.