The coronavirus disease 2019 (COVID-19) is a pandemic disease declared by the World Health Organization (WHO) that was spread globally. The novel coronavirus disease is named Severe Acute Respiratory Syndrome Coronavirus (SARS-COV2) is a mild to severe respiratory disease having fever, cough, and shortness of breath as initial symptoms. This virus disseminates through contact with infectious persons, touching contaminated surfaces, and infectious air droplets. The virus invades into healthy cells of the body especially the lungs causing the respiratory problems and sometimes causes organ failure by killing healthy cells which eventually leads to death. The origin of coronavirus disease was zoonotic, as the initial cases had been reported from animals in Wuhan. The research challenges in COVID-19 are related to the identification, diagnosis of clinical characteristics of COVID-19 patients, and provide an effective treatment of the COVID infected patients.