Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner.
Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner.
Jim Riviere, DVM, PhD, DSc (hon), ATS, is the Burroughs Wellcome Fund Distinguished Professor of Pharmacology, Alumni Distinguished Graduate Professor, and Director of the Center for Chemical Toxicology Research and Pharmacokinetics at North Carolina State University, and Editor of the Journal of Veterinary Pharmacology and Therapeutics.
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Preface. Chapter 1: Introduction. Chapter 2: Principles of Drug Movement in the Body. Chapter 3: Quantitative Structure Permeability Relationships (QSPeR). Chapter 4: Absorption. Chapter 5: Distribution. Chapter 6: Renal Elimination. Chapter 7: Hepatic Biotransformation and Biliary Excretion. Chapter 8: Compartmental Models. Chapter 9: Noncompartmental Models. Chapter 10: Nonlinear Models. Chapter 11: Physiological Models. Chapter 12: Dosage Regimens. Chapter 13: Simultaneous Pharmacokinetic-Pharmacodynamic Modeling. Chapter 14: Study Design and Data Analysis. Chapter 15: Design and Analysis of Bioequivalence Studies and FDA's in vitro/in vivo (IVIV). Chapter 16: Population Pharmacokinetic Models and the Bayesian Forecasting Applied to Clincal Pharmacokinetics. Chapter 17: Dosage Adjustments in Renal (and Hepatic) Disease. Chapter 18: Interspecies Extrapolations. Chapter 19: Tissue Residues and Withdrawal TimesAppendix
