Comprehensive Organic Transformations, 4 Volume Set
A Guide to Functional Group Preparations
Herausgeber: Larock, Richard C
Comprehensive Organic Transformations, 4 Volume Set
A Guide to Functional Group Preparations
Herausgeber: Larock, Richard C
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Die wesentlich erweiterte Neuauflage dieses Bestsellers bietet eine enzyklopädische und systematische Sammlung nützlicher synthetischer Methoden, inkl. zehntausende Reaktionen und synthetische Transformationen. Frühere Auflagen wurden von der Fachpresse hochgelobt.
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Produktdetails
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- Verlag: John Wiley & Sons / Wiley
- 3rd Revised edition
- Seitenzahl: 4056
- Erscheinungstermin: 20. März 2018
- Englisch
- Abmessung: 279mm x 554mm x 221mm
- Gewicht: 8732g
- ISBN-13: 9780470927953
- ISBN-10: 047092795X
- Artikelnr.: 43412604
- Verlag: John Wiley & Sons / Wiley
- 3rd Revised edition
- Seitenzahl: 4056
- Erscheinungstermin: 20. März 2018
- Englisch
- Abmessung: 279mm x 554mm x 221mm
- Gewicht: 8732g
- ISBN-13: 9780470927953
- ISBN-10: 047092795X
- Artikelnr.: 43412604
Richard C. Larock, PhD, is Professor Emeritus of Chemistry at Iowa State University. He is a pioneer in the use of palladium catalysts in organic synthesis, particularly in the synthesis of carbocycles and heterocycles. Dr. Larock has given over 420 research presentations and published about 350 articles, 32 patents, and 4 books including two editions of the bestselling classic Comprehensive Organic Transformations (Wiley 1996 and 1999).
Literature Abbreviations xxxix Chemical Abbreviations xlix Alkanes and Arenes 1 General References 3 1. Reduction 5 2. Coupling Reactions 193 3. Friedel-Crafts and Related Alkylation Reactions 343 4. Ring-Forming Reactions 355 5. Aromatization 467 Alkenes 519 General References 521 1. Isomerization of Alkenes 523 2. Elimination 571 3. Alkylidenation of Carbonyl and Related Compounds 645 4. Wittig and Related Reactions 661 5. Metal-Promoted Coupling Reactions 693 6. Arene, Alkyne, and Diene Addition Reactions 767 7. Dienes and Polyenes 879 8. Diels-Alder Reactions 1017 9. Cyclization, Annulation, and Related Reactions 1105 Alkynes 1143 General References 1145 1. Isomerization and Metathesis 1147 2. Elimination Reactions 1151 3. Wittig and Related Approaches 1169 4. Alkylation, Alkenylation, and Arylation of Alkynes and Allenes 1175 Halides 1231 General References 1233 1. Halogenation of Hydrocarbons 1237 3. Halogenation of Alkenes and Dienes 1269 4. Halogenation of Alkynes 1313 5. Interconversion of Halides 1333 6. Halogenation of Nitrogen Compounds 1345 7. Halogenation of Ethers 1355 8. Halogenation of Alcohols 1361 9. Halogenation of Phenols 1385 10. Halogenation of Sulfur and Selenium Compounds 1387 11. Halogenation of Carbonyl and Related Compounds 1397 12. Halodecarboxylation and Decarbonylation of Acids and Derivatives 1459 13. Halogenation of Organometallics 1467 Amines 1479 General References 1481 1. From Alkanes 1483 2. From Arenes 1487 3. From Alkenes, Dienes, and Alkynes 1491 4. From Alkyl and Aryl Halides Or Sulfonates 1529 5. From Other Amines and Derivatives 1545 6. From Azides 1595 7. From Nitro Compounds 1605 8. Heteroatom and Metal Substitution 1617 9. From Ethers, Alcohols, and Derivatives 1621 10. From Aldehydes, Ketones, and Derivatives 1631 11. From Carboxylic Acids and Derivatives 1697 12. From Nitriles 1709 13. From Isonitriles and Azo Compounds 1715 Ethers 1717 General References 1719 1. From Other Ethers 1721 2. Alkylation of Alcohols, Phenols, and Derivatives 1743 3. Alkane, Arene, Alkene, and Alkyne Substitutions and Additions 1859 4. Acetal, Carbonyl, and Ortho Ester Conversions 1963 5. Miscellaneous Reactions 2053 Alcohols and Phenols 2057 General References 2059 1. Resolution 2061 2. Alcohol Transposition 2067 3. Substitution 2071 4. Oxidation 2083 5. Alkene, Diene, and Alkyne Additions 2107 6. Organoboranes 2143 7. Ether Cleavage 2163 8. Reduction 2269 9. Alkylation of Carbonyl Compounds 2339 10. Miscellaneous Reactions 2437 Aldehydes and Ketones 2439 General References 2441 1. Carbonyl Transposition 2443 2. Oxidation 2449 3. Reduction of Phenols, Carboxylic Acids and Derivatives, and Nitriles 2587 4. Rearrangements 2605 5. Condensation Reactions 2687 6. Cyclization and Annulation Reactions 2721 7. Carbonylation and Related Reactions 2783 8. Electrophilic Acylation 2831 9. Nucleophilic Acylation 2927 10. Sulfur, Selenium, and Tellurium Reagents 2949 11. Heterocycles 2961 12. Carbonyl Homologation 2969 13. Alkylation and Acylation of Aldehydes, Ketones,And Their Derivatives 2981 15. 1,4-Addition To
,
-Unsaturated Carbonyl Compounds and Derivatives 3141 Nitriles, Carboxylic Acids, and Derivatives 3243 General References 3245 1. Oxidation, Substitution, and Addition 3247 2. Reduction 3331 3. Carbonylation, Carboxylation, and Related Reactions 3335 4. Carbonyl Homologation and Degradation 3399 5. Alkylation, Acylation, and Substitution of Nitriles, Carboxylic Acids, and Derivatives 3409 6. Conjugate Addition To
,
-Unsaturated Nitriles, Carboxylic Acids, and Derivatives 3549 7. Rearrangements 3619 8. Lactone and Lactam Formation 3647 9. Interconversion of Nitriles, Carboxylic Acids, and Derivatives 3749 10. Miscellaneous Reactions 3831
,
-Unsaturated Carbonyl Compounds and Derivatives 3141 Nitriles, Carboxylic Acids, and Derivatives 3243 General References 3245 1. Oxidation, Substitution, and Addition 3247 2. Reduction 3331 3. Carbonylation, Carboxylation, and Related Reactions 3335 4. Carbonyl Homologation and Degradation 3399 5. Alkylation, Acylation, and Substitution of Nitriles, Carboxylic Acids, and Derivatives 3409 6. Conjugate Addition To
,
-Unsaturated Nitriles, Carboxylic Acids, and Derivatives 3549 7. Rearrangements 3619 8. Lactone and Lactam Formation 3647 9. Interconversion of Nitriles, Carboxylic Acids, and Derivatives 3749 10. Miscellaneous Reactions 3831
Literature Abbreviations xxxix Chemical Abbreviations xlix Alkanes and Arenes 1 General References 3 1. Reduction 5 2. Coupling Reactions 193 3. Friedel-Crafts and Related Alkylation Reactions 343 4. Ring-Forming Reactions 355 5. Aromatization 467 Alkenes 519 General References 521 1. Isomerization of Alkenes 523 2. Elimination 571 3. Alkylidenation of Carbonyl and Related Compounds 645 4. Wittig and Related Reactions 661 5. Metal-Promoted Coupling Reactions 693 6. Arene, Alkyne, and Diene Addition Reactions 767 7. Dienes and Polyenes 879 8. Diels-Alder Reactions 1017 9. Cyclization, Annulation, and Related Reactions 1105 Alkynes 1143 General References 1145 1. Isomerization and Metathesis 1147 2. Elimination Reactions 1151 3. Wittig and Related Approaches 1169 4. Alkylation, Alkenylation, and Arylation of Alkynes and Allenes 1175 Halides 1231 General References 1233 1. Halogenation of Hydrocarbons 1237 3. Halogenation of Alkenes and Dienes 1269 4. Halogenation of Alkynes 1313 5. Interconversion of Halides 1333 6. Halogenation of Nitrogen Compounds 1345 7. Halogenation of Ethers 1355 8. Halogenation of Alcohols 1361 9. Halogenation of Phenols 1385 10. Halogenation of Sulfur and Selenium Compounds 1387 11. Halogenation of Carbonyl and Related Compounds 1397 12. Halodecarboxylation and Decarbonylation of Acids and Derivatives 1459 13. Halogenation of Organometallics 1467 Amines 1479 General References 1481 1. From Alkanes 1483 2. From Arenes 1487 3. From Alkenes, Dienes, and Alkynes 1491 4. From Alkyl and Aryl Halides Or Sulfonates 1529 5. From Other Amines and Derivatives 1545 6. From Azides 1595 7. From Nitro Compounds 1605 8. Heteroatom and Metal Substitution 1617 9. From Ethers, Alcohols, and Derivatives 1621 10. From Aldehydes, Ketones, and Derivatives 1631 11. From Carboxylic Acids and Derivatives 1697 12. From Nitriles 1709 13. From Isonitriles and Azo Compounds 1715 Ethers 1717 General References 1719 1. From Other Ethers 1721 2. Alkylation of Alcohols, Phenols, and Derivatives 1743 3. Alkane, Arene, Alkene, and Alkyne Substitutions and Additions 1859 4. Acetal, Carbonyl, and Ortho Ester Conversions 1963 5. Miscellaneous Reactions 2053 Alcohols and Phenols 2057 General References 2059 1. Resolution 2061 2. Alcohol Transposition 2067 3. Substitution 2071 4. Oxidation 2083 5. Alkene, Diene, and Alkyne Additions 2107 6. Organoboranes 2143 7. Ether Cleavage 2163 8. Reduction 2269 9. Alkylation of Carbonyl Compounds 2339 10. Miscellaneous Reactions 2437 Aldehydes and Ketones 2439 General References 2441 1. Carbonyl Transposition 2443 2. Oxidation 2449 3. Reduction of Phenols, Carboxylic Acids and Derivatives, and Nitriles 2587 4. Rearrangements 2605 5. Condensation Reactions 2687 6. Cyclization and Annulation Reactions 2721 7. Carbonylation and Related Reactions 2783 8. Electrophilic Acylation 2831 9. Nucleophilic Acylation 2927 10. Sulfur, Selenium, and Tellurium Reagents 2949 11. Heterocycles 2961 12. Carbonyl Homologation 2969 13. Alkylation and Acylation of Aldehydes, Ketones,And Their Derivatives 2981 15. 1,4-Addition To
,
-Unsaturated Carbonyl Compounds and Derivatives 3141 Nitriles, Carboxylic Acids, and Derivatives 3243 General References 3245 1. Oxidation, Substitution, and Addition 3247 2. Reduction 3331 3. Carbonylation, Carboxylation, and Related Reactions 3335 4. Carbonyl Homologation and Degradation 3399 5. Alkylation, Acylation, and Substitution of Nitriles, Carboxylic Acids, and Derivatives 3409 6. Conjugate Addition To
,
-Unsaturated Nitriles, Carboxylic Acids, and Derivatives 3549 7. Rearrangements 3619 8. Lactone and Lactam Formation 3647 9. Interconversion of Nitriles, Carboxylic Acids, and Derivatives 3749 10. Miscellaneous Reactions 3831
,
-Unsaturated Carbonyl Compounds and Derivatives 3141 Nitriles, Carboxylic Acids, and Derivatives 3243 General References 3245 1. Oxidation, Substitution, and Addition 3247 2. Reduction 3331 3. Carbonylation, Carboxylation, and Related Reactions 3335 4. Carbonyl Homologation and Degradation 3399 5. Alkylation, Acylation, and Substitution of Nitriles, Carboxylic Acids, and Derivatives 3409 6. Conjugate Addition To
,
-Unsaturated Nitriles, Carboxylic Acids, and Derivatives 3549 7. Rearrangements 3619 8. Lactone and Lactam Formation 3647 9. Interconversion of Nitriles, Carboxylic Acids, and Derivatives 3749 10. Miscellaneous Reactions 3831