Computational Biophysics of Membrane Proteins

Herausgeber: Domene, Carmen

• Gebundenes Buch

Produktbeschreibung

Exploring current themes in modern computational and membrane protein biophysics, this book presents a comprehensive account of the fundamental principles underlying different methods and techniques used to describe the intriguing mechanisms by which membrane proteins function. The book discusses the experimental approaches employed to study these proteins, with chapters reviewing recent crucial structural advances that have allowed computational biophysicists to discern how these molecular machines work. The book then explores what computational methods are available to researchers and what these have taught us about three key families of membrane proteins: ion channels, transporters and receptors. The book is ideal for researchers in computational chemistry and computational biophysics.

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Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 274
• Erscheinungstermin: 5. Dezember 2016
• Englisch
• Abmessung: 236mm x 160mm x 20mm
• Gewicht: 544g
• ISBN-13: 9781782624905
• ISBN-10: 1782624902
• Artikelnr.: 45467179

Autorenporträt

Carmen Domene is a Reader in Computational Chemistry at King's College London, UK. Her research group applies principles from quantum mechanics and statistical thermodynamics to model biomolecular phenomena with computer simulations.

Inhaltsangabe

Introduction to the Structural Biology of Membrane Proteins
Molecular Dynamics Simulations: Principles and Applications for the Study of Membrane Proteins
Free Energy Calculations for Understanding Membrane Receptors
Non-atomistic Simulations of Ion Channels
Experimental and Computational Approaches to Study Membranes and Lipid-Protein Interactions
Computer Simulation of Ion Channels
Computational Characterization of Molecular Mechanisms of Membrane Transporter Function
Computational Studies of Receptors