A description of fundamental and applied aspects of the usefulness of computations when approaching protein-protein interactions, this book incorporates different views of the same biochemical problem from sequence to structure to energetics. It covers protein-protein interaction prediction and dynamics, design, drug design for inhibition, and uses for predicting function. The text provides an overview of the topic with general chapters understandable by students and junior researches in this area, while also providing advanced material for more specialized readers. The chapters detail the…mehr
A description of fundamental and applied aspects of the usefulness of computations when approaching protein-protein interactions, this book incorporates different views of the same biochemical problem from sequence to structure to energetics. It covers protein-protein interaction prediction and dynamics, design, drug design for inhibition, and uses for predicting function. The text provides an overview of the topic with general chapters understandable by students and junior researches in this area, while also providing advanced material for more specialized readers. The chapters detail the complexity of protein interaction studies and inform readers of potential caveats that might be involved.
Computational design of protein-protein interactions. Molecular Mimicry and Competitive Recruitment. Intrinsically unstructured proteins. The molecular architecture of protein-protein binding sites. Characteristic of protein-protein recognition. Protein-Protein Docking. Identification of hot spots within druggable binding regions. Hot-spot mimicry of ac cytokine receptor. Chaperone-related immune dysfunction. Recognition proteins of the innate immune system. Epitope mapping using combinatorial phage-display libraries. Identification of conserved protein complexes based on a model of protein network evolution. Interaction sites identified from sequences. Thermophilic Protein Complex Stabilized by Topological Interlinked. Protein interface recognition for structural proteomics. Strategies to search and design stabilizers of protein-protein interactions. Dynamics and allostery in protein-protein interactions.
Computational design of protein-protein interactions. Molecular Mimicry and Competitive Recruitment. Intrinsically unstructured proteins. The molecular architecture of protein-protein binding sites. Characteristic of protein-protein recognition. Protein-Protein Docking. Identification of hot spots within druggable binding regions. Hot-spot mimicry of ac cytokine receptor. Chaperone-related immune dysfunction. Recognition proteins of the innate immune system. Epitope mapping using combinatorial phage-display libraries. Identification of conserved protein complexes based on a model of protein network evolution. Interaction sites identified from sequences. Thermophilic Protein Complex Stabilized by Topological Interlinked. Protein interface recognition for structural proteomics. Strategies to search and design stabilizers of protein-protein interactions. Dynamics and allostery in protein-protein interactions.
Es gelten unsere Allgemeinen Geschäftsbedingungen: www.buecher.de/agb
Impressum
www.buecher.de ist ein Shop der buecher.de GmbH & Co. KG Bürgermeister-Wegele-Str. 12, 86167 Augsburg Amtsgericht Augsburg HRA 13309
