Arithmetic logical unit compares several accumulators and registers them. It derives all the data from the main memory as directed by CU (control unit) based on a computer language program. Some logical operations of the Arithmetic Logical Unit enable the computer to have quality decision-making.It's also known as the computer's principal or primary memory because, like human memory, it can store information that can be remembered when needed. The instruction program must be stored in the main memory to make it work automatically. Bioinformatics is a stream that uses computational techniques to collect, store, analyze and integrate biological data. This data is based on different techniques, which include mapping genes, sequencing of genomes, nucleic acids and other related macro and micro biomolecules.