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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Conjugate gaze palsy refers to an inability of both eyes to move in the same direction at the same time. It can be associated with a lesion of the paramedian pontine reticular formation. The paramedian pontine reticular formation, or PPRF, is part of the pontine reticular formation, a brain region without clearly defined borders in the center of the pons. It is involved in the coordination of eye movements, particularly horizontal gaze and saccades.